Sugi Predict

Sugi Predict / Compounds / SCHEMBL703690

SCHEMBL703690

SCHEMBL703690

CCCCCCCCCCCCCCCCOC[C@H](COP(=O)([O-])OCC[N+](C)(C)C)OCCCCCCCCC(=O)O

nearest known ligand 0.81

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ RECQL P46063 1/20 0.81
▸ MAPK1 P28482 4/20 0.70
▸ MEN1 O00255 3/20 0.70
▸ GMNN O75496 3/20 0.70
▸ LMNA P02545 3/20 0.70
▸ BLM P54132 3/20 0.70
▸ KMT2A Q03164 3/20 0.70
▸ NPSR1 Q6W5P4 3/20 0.70
▸ SMN1; SMN2 Q16637 2/20 0.70
▸ PRKD3 O94806 1/20 0.70
▸ PRKCG P05129 1/20 0.70
▸ PRKCB P05771 1/20 0.70
▸ PRKCA P17252 1/20 0.70
▸ PRKCH P24723 1/20 0.70
▸ AKT1 P31749 1/20 0.70
▸ PRKCI P41743 1/20 0.70
▸ PRKCE Q02156 1/20 0.70
▸ PRKCQ Q04759 1/20 0.70
▸ PRKCZ Q05513 1/20 0.70
▸ PRKCD Q05655 1/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2231559 1.00 RECQL (0.81) RECQLMAPK1MEN1GMNNLMNA
SCHEMBL1963192 1.00 RECQL (0.81) RECQLMAPK1MEN1GMNNLMNA
Vb-201 SCHEMBL14322398 1.00 RECQL (0.81) RECQLMAPK1MEN1GMNNLMNA
SCHEMBL2232585 1.00 RECQL (0.81) RECQLMAPK1MEN1GMNNLMNA
Vb-201 SCHEMBL2071110 1.00 RECQL (0.81) RECQLMAPK1MEN1GMNNLMNA
SCHEMBL704033 1.00 RECQL (0.81) RECQLMAPK1MEN1GMNNLMNA
SCHEMBL20143296 1.00 RECQL (0.81) RECQLMAPK1MEN1GMNNLMNA
SCHEMBL704034 1.00 RECQL (0.81) RECQLMAPK1MEN1GMNNLMNA
Vb-201 SCHEMBL2071230 1.00 RECQL (0.81) RECQLMAPK1MEN1GMNNLMNA
SCHEMBL2232633 1.00 RECQL (0.81) RECQLMAPK1MEN1GMNNLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9968622-B2 High-purity phospholipids VASCULAR BIOGENICS LTD. (IL) 2018-05-15 — — US disclosed
US-20170246197-A1 High-Purity Phospholipids VASCULAR BIOGENICS LTD. (IL) 2017-08-31 — — US disclosed
US-9566288-B2 High-purity phospholipids VASCULAR BIOGENICS LTD. (IL) 2017-02-14 — — US disclosed
US-20150216882-A1 High-Purity Phospholipids VASCULAR BIOGENICS LTD. (IL) 2015-08-06 — — US disclosed
US-9006217-B2 High-purity phospholipids VASCULAR BIOGENICS LTD. (IL) 2015-04-14 — — US disclosed
US-8802875-B2 Process for the preparation of oxidized phospholipids VASCULAR BIOGENICS LTD. (IL) 2014-08-12 — — US disclosed
US-8759557-B2 Process for the preparation of oxidized phospholipids VASCULAR BIOGENICS LTD. (IL) 2014-06-24 — — US disclosed
US-8569529-B2 High-purity phospholipids VASCULAR BIOGENICS LTD. (IL) 2013-10-29 — — US disclosed
US-20130237720-A1 High-Purity Phospholipids VASCULAR BIOGENICS LTD. (IL) 2013-09-12 — — US disclosed
US-20130190523-A1 Process for the Preparation of Oxidized Phospholipids VASCULAR BIOGENICS LTD. (IL) 2013-07-25 — — US disclosed
US-20130158283-A1 Process for the Preparation of Oxidized Phospholipids VASCULAR BIOGENICS LTD. (IL) 2013-06-20 — — US disclosed
US-20130079540-A1 High-Purity Phospholipids VASCULAR BIOGENICS LTD. (IL) 2013-03-28 — — US disclosed
EP-2522672-A1 Oxidized phospholipids Vascular Biogenics Ltd. (IL) 2012-11-14 — — EP disclosed
US-20120130108-A1 PROCESS FOR THE PREPARATION OF OXIDIZED PHOSPHOLIPIDS VASCULAR BIOGENICS LTD. (IL) 2012-05-24 — — US disclosed
US-8124800-B2 Process for the preparation of oxidized phospholipids VASCULAR BIOGENICS LTD. (IL) 2012-02-28 — — US disclosed
US-20100317881-A1 PROCESS FOR THE PREPARATION OF OXIDIZED PHOSPHOLIPIDS VASCULAR BIOGENICS LTD. (IL) 2010-12-16 — — US disclosed
US-7807847-B2 Process for the preparation of oxidized phospholipids VASCULAR BIOGENICS LTD. (IL) 2010-10-05 — — US disclosed
US-20070112211-A1 Process for the preparation of oxidized phospholipids VASCULAR BIOGENICS LTD. (IL) 2007-05-17 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130190523-A1 Process for the Preparation of Oxidized Phospholipids PHOSPHO1, SGMS1, SGMS2 RECQL 2928/4885MAPK1 1798/4885MEN1 2767/4885
US-20100317881-A1 PROCESS FOR THE PREPARATION OF OXIDIZED PHOSPHOLIPIDS PHOSPHO1, SGMS1, SGMS2 RECQL 2755/4885MAPK1 1784/4885MEN1 2727/4885
US-20130079540-A1 High-Purity Phospholipids PHOSPHO1, SGMS1, SGMS2 RECQL 3038/4885MAPK1 1544/4885MEN1 3752/4885
US-20150216882-A1 High-Purity Phospholipids PHOSPHO1, SGMS1, SGMS2 RECQL 2816/4885MAPK1 1510/4885MEN1 3857/4885
US-20130158283-A1 Process for the Preparation of Oxidized Phospholipids PHOSPHO1, SGMS1, SGMS2 RECQL 2755/4885MAPK1 1784/4885MEN1 2727/4885
US-20170246197-A1 High-Purity Phospholipids PHOSPHO1, SGMS1, SGMS2 RECQL 2816/4885MAPK1 1510/4885MEN1 3857/4885
US-20120130108-A1 PROCESS FOR THE PREPARATION OF OXIDIZED PHOSPHOLIPIDS PHOSPHO1, SGMS1, SGMS2 RECQL 2755/4885MAPK1 1784/4885MEN1 2727/4885
US-20070112211-A1 Process for the preparation of oxidized phospholipids PHOSPHO1, SGMS1, SGMS2 RECQL 2755/4885MAPK1 1784/4885MEN1 2727/4885
US-20130237720-A1 High-Purity Phospholipids PHOSPHO1, SGMS1, SGMS2 RECQL 2816/4885MAPK1 1510/4885MEN1 3857/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.