Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.53 |
| ▸ | MMP9 | P14780 | 2/20 | 0.51 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.51 |
| ▸ | MMP2 | P08253 | 1/20 | 0.51 |
| ▸ | MMP8 | P22894 | 1/20 | 0.51 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.47 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | FCER2 | P06734 | 1/20 | 0.47 |
| ▸ | MMP3 | P08254 | 1/20 | 0.47 |
| ▸ | TPH1 | P17752 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | MME | P08473 | 1/20 | 0.45 |
| ▸ | ACE | P12821 | 1/20 | 0.45 |
| ▸ | CPA1 | P15085 | 1/20 | 0.45 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.45 |
| ▸ | GRN | P28799 | 1/20 | 0.44 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.44 |
| ▸ | MGAM | O43451 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7037002 | 1.00 | ACACB (0.53) | ACACBMMP9NTSR1MMP2MMP8 | |
| SCHEMBL31369492 | 0.87 | MMP9 (0.53) | ACACBMMP9NTSR1MMP2MMP8 | |
| SCHEMBL31688534 | 0.87 | MMP9 (0.53) | ACACBMMP9NTSR1MMP2MMP8 | |
| SCHEMBL5782434 | 0.84 | ACACB (0.57) | ACACBFCER2LMNAPPARGMME | |
| SCHEMBL31407825 | 0.83 | ACE (0.58) | MMP9MMP1FCER2MMP3PPARG | |
| SCHEMBL7857022 | 0.83 | ACE (0.58) | MMP9MMP1FCER2MMP3PPARG | |
| SCHEMBL9743160 | 0.83 | ACE (0.58) | MMP9MMP1FCER2MMP3PPARG | |
| SCHEMBL2638376 | 0.81 | ACACB (0.55) | ACACBMMP9MMP2MMP8MMP1 | |
| SCHEMBL7862749 | 0.81 | ACACB (0.52) | ACACBMMP9MMP2MMP8MMP1 | |
| SCHEMBL2638379 | 0.81 | ACACB (0.52) | ACACBMMP9MMP2MMP8MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0822827-B1 | ANTAGONISTS OF LHRH | UNIV TEXAS (US) | 2003-03-05 | — | — | EP | disclosed |