Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.56 |
| ▸ | PI4KA | P42356 | 1/20 | 0.56 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.56 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.56 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.56 |
| ▸ | DOT1L | Q8TEK3 | 3/20 | 0.55 |
| ▸ | AHCY | P23526 | 1/20 | 0.51 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.51 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.51 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.51 |
| ▸ | AMD1 | P17707 | 2/20 | 0.47 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7037427 | 0.90 | RXFP1 (0.51) | RXFP1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL9970273 | 0.86 | DOT1L (0.69) | RXFP1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL9970168 | 0.86 | DOT1L (0.69) | RXFP1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL2288521 | 0.84 | RXFP1 (0.58) | RXFP1 | |
| SCHEMBL31533316 | 0.83 | RXFP1 (0.51) | RXFP1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL31659112 | 0.83 | RXFP1 (0.49) | RXFP1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL7039480 | 0.83 | RXFP1 (0.51) | RXFP1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL9970202 | 0.81 | DOT1L (0.61) | RXFP1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL15829716 | 0.81 | DOT1L (0.61) | RXFP1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL9970625 | 0.81 | DOT1L (0.73) | RXFP1PI4KAPI4K2BPI4K2API4KB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991412-B1 | AMINOACYL SULFAMIDES FOR THE TREATMENT OF HYPERPROLIFERATIVE DISORDERS | CUBIST PHARM INC (US) | 2003-03-12 | — | — | EP | disclosed |
| US-5824657-A | ANTICARCINOGENIC AGENTS, SKIN DISORDERS AND PSORIASIS | CUBIST PHARMACEUTICALS, INC. (US) | 1998-10-20 | — | — | US | disclosed |