Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | PI4KA | P42356 | 1/20 | 0.49 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.49 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.49 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.49 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.45 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.45 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.45 |
| ▸ | DOT1L | Q8TEK3 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31533316 | 1.00 | RXFP1 (0.51) | RXFP1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL7031903 | 0.91 | LMNA (0.41) | RXFP1P2RX3P2RX4 | |
| SCHEMBL7036534 | 0.89 | RXFP1 (0.46) | RXFP1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL7037427 | 0.86 | RXFP1 (0.51) | RXFP1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL31533317 | 0.85 | RXFP1 (0.53) | RXFP1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL7037167 | 0.83 | RXFP1 (0.56) | RXFP1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL30239003 | 0.83 | RXFP1 (0.43) | RXFP1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL31001565 | 0.82 | P2RX3 (0.49) | RXFP1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL30239335 | 0.80 | DOT1L (0.50) | RXFP1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL26530697 | 0.79 | PI4KA (0.55) | RXFP1PI4KAPI4K2BPI4K2API4KB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991412-B1 | AMINOACYL SULFAMIDES FOR THE TREATMENT OF HYPERPROLIFERATIVE DISORDERS | CUBIST PHARM INC (US) | 2003-03-12 | — | — | EP | disclosed |
| US-5824657-A | ANTICARCINOGENIC AGENTS, SKIN DISORDERS AND PSORIASIS | CUBIST PHARMACEUTICALS, INC. (US) | 1998-10-20 | — | — | US | disclosed |