Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 8/20 | 0.47 |
| ▸ | HTR2C | P28335 | 2/20 | 0.32 |
| ▸ | HTR2B | P41595 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7037375 | 1.00 | HIF1A (0.47) | HIF1AHTR2CHTR2BALDH1A1HTR2A | |
| SCHEMBL7034704 | 0.91 | HIF1A (0.37) | HIF1AHTR2CHTR2BALDH1A1HTR2A | |
| SCHEMBL7036501 | 0.89 | HIF1A (0.47) | HIF1AALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL7038200 | 0.89 | HIF1A (0.47) | HIF1AALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL7209943 | 0.89 | HIF1A (0.47) | HIF1AALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL7030189 | 0.89 | HIF1A (0.47) | HIF1AALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL6156049 | 0.81 | HIF1A (0.48) | HIF1AALDH1A1MAPTPKM | |
| SCHEMBL6156045 | 0.81 | HIF1A (0.48) | HIF1AALDH1A1MAPTPKM | |
| SCHEMBL7707860 | 0.81 | HIF1A (0.48) | HIF1AALDH1A1MAPTPKM | |
| SCHEMBL7028003 | 0.81 | HIF1A (0.38) | HIF1AALDH1A1MEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1286955-A1 | ARYL AND HETEROARYLCYCLOPROPYL OXIME ETHERS AND THEIR USE AS FUNGICIDES | Dow AgroSciences LLC (US) | 2003-03-05 | — | — | EP | disclosed |
| WO-2001087826-A1 | ARYL AND HETEROARYLCYCLOPROPYL OXIME ETHERS AND THEIR USE AS FUNGICIDES | ROHM AND HAAS COMPANY (US) | 2001-11-22 | — | — | WO | disclosed |