Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | UPP1 | Q16831 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.34 |
| ▸ | LGALS4 | P56470 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7038041 | 0.95 | UPP1 (0.39) | HPGDUPP1POLBCHRNB2CHRNA5 | |
| SCHEMBL7038066 | 0.91 | MEN1 (0.41) | UPP1POLBCHRNB2CHRNA5CHRNA7 | |
| SCHEMBL7035235 | 0.88 | HPGD (0.39) | HPGDUPP1POLBCHRNB2CHRNA5 | |
| SCHEMBL7030197 | 0.87 | ALDH1A1 (0.44) | HPGDUPP1KMT2ACYP1A2CYP2C19 | |
| SCHEMBL7035707 | 0.84 | POLB (0.36) | HPGDUPP1POLBCHRNB2CHRNA5 | |
| SCHEMBL8429073 | 0.84 | POLB (0.35) | HPGDUPP1POLBCHRNB2CHRNA5 | |
| SCHEMBL7031856 | 0.83 | POLB (0.35) | HPGDUPP1POLBCHRNB2CHRNA5 | |
| SCHEMBL7037180 | 0.83 | UPP1 (0.37) | HPGDUPP1POLBCHRNB2CHRNA5 | |
| SCHEMBL8427016 | 0.81 | NT5E (0.39) | HPGDUPP1POLBKMT2AMEN1 | |
| SCHEMBL7161077 | 0.81 | ALDH1A1 (0.39) | CHRNB2CHRNA5CHRNA7CHRNA4NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0842942-B1 | D-PENTOFURANOSE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | TAIHO PHARMACEUTICAL CO LTD (JP) | 2003-03-12 | — | — | EP | disclosed |
| US-5880294-A | D-pentofuranose derivatives and process for preparing the same | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1999-03-09 | — | — | US | disclosed |
| EP-0842942-A1 | D-PENTOFURANOSE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | TAIHO PHARMACEUTICAL COMPANY, LIMITED (JP) | 1998-05-20 | — | — | EP | disclosed |