Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.51 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.51 |
| ▸ | DAO | P14920 | 1/20 | 0.50 |
| ▸ | PDE4A | P27815 | 1/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.48 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.48 |
| ▸ | CETP | P11597 | 5/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.39 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5537495 | 0.84 | CHRM2 (0.55) | CHRM2CHRM1CHRM3DAOCETP | |
| SCHEMBL102840 | 0.83 | CETP (0.48) | CHRM2CHRM1CHRM3DAOCETP | |
| SCHEMBL4714751 | 0.80 | PDE4A (0.46) | MEN1KMT2ADAOPDE4APDE4B | |
| SCHEMBL2095982 | 0.78 | CHRM2 (0.55) | CHRM2CHRM1CHRM3DAOCETP | |
| SCHEMBL1047406 | 0.78 | CHRM2 (0.58) | CHRM2CHRM1CHRM3DAOCETP | |
| SCHEMBL3119286 | 0.78 | CHRM2 (0.55) | CHRM2CHRM1CHRM3DAOCETP | |
| SCHEMBL2090888 | 0.78 | CHRM2 (0.58) | CHRM2CHRM1CHRM3DAOCETP | |
| SCHEMBL2090884 | 0.78 | CHRM2 (0.55) | CHRM2CHRM1CHRM3DAOCETP | |
| SCHEMBL1095907 | 0.78 | TAAR1 (0.61) | CHRM2CHRM1CHRM3DAOCETP | |
| SCHEMBL1047407 | 0.78 | CYP4F2 (0.56) | CHRM2CHRM1CHRM3DAOCETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119462506-A | Long-chain ketonitrile compound and preparation method and application thereof | 华东理工大学 | 2025-02-18 | — | — | CN | disclosed |
| CN-115636743-A | Preparation method of phenylacetic acid compound | 上海历赢生物科技有限公司 | 2023-01-24 | — | — | CN | disclosed |
| EP-2343298-B9 | Heteroaryl substituted pyrrolo[2,3-b]pyridines and pyrrolo[2,3-b]pyrimidines as Janus kinase inhibitors | INCYTE HOLDINGS CORP (US) | 2020-05-06 | — | — | EP | disclosed |
| CN-101663262-A | N- (3-benzyl) -2, 2- (diphenyl) -propan-1-amine derivatives as CETP inhibitors for the treatment of atherosclerosis and cardiovascular diseases | BRISTOL MYERS SQUIBB CO | 2010-03-03 | — | — | CN | disclosed |
| US-20030236276-A1 | Pyrrolo[2.1-a]isoquinoline derivatives | NIEWOHNER ULRICH (DE) | 2003-12-25 | — | — | US | disclosed |
| WO-2003014116-A1 | PYRROLO[2.1-A]ISOQUINOLINE DERIVATIVES | BAYER CORPORATION (US) | 2003-02-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030236276-A1 | Pyrrolo[2.1-a]isoquinoline derivatives | PDE5A, PDE2A, PDE3A | MEN1 2332/4885KMT2A 2561/4885CHRM2 3249/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.