Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
| ▸ | DAO | P14920 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5544520 | 0.81 | DAO (0.48) | DAOGPR84ALDH1A1TSHRSLC6A4 | |
| SCHEMBL549086 | 0.81 | ALDH1A1 (0.44) | DAOMEN1KMT2AALDH1A1TSHR | |
| SCHEMBL7038656 | 0.80 | MEN1 (0.59) | PDE4APDE4BPDE4CPDE4DDAO | |
| Hydrochloric Acid SCHEMBL16564135 | 0.79 | ALDH1A1 (0.42) | DAOMEN1KMT2AALDH1A1TSHR | |
| Iodide SCHEMBL30828284 | 0.79 | ALDH1A1 (0.42) | DAOMEN1KMT2AALDH1A1TSHR | |
| SCHEMBL13537015 | 0.79 | MEN1 (0.40) | PDE4APDE4BPDE4CPDE4DMEN1 | |
| Acetonitrile SCHEMBL28224520 | 0.77 | SLC6A4 (0.43) | DAOMEN1KMT2AGPR84ALDH1A1 | |
| SCHEMBL6825071 | 0.77 | DAO (0.41) | DAOMEN1KMT2AGPR84ALDH1A1 | |
| SCHEMBL8764230 | 0.77 | MEN1 (0.64) | PDE4APDE4BPDE4CPDE4DMEN1 | |
| SCHEMBL3142341 | 0.76 | CA2 (0.41) | PDE4APDE4BPDE4CPDE4DMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1337517-B1 | PYRIMIDINONE DERIVATIVES AND THEIR USE IN THE TREATMENT OF ATHEROSCLEROSIS | SMITHKLINE BEECHAM PLC (GB) | 2008-11-26 | — | — | EP | disclosed |