Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.74 |
| ▸ | HPGD | P15428 | 5/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.74 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | ESR1 | P03372 | 5/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | USP2 | O75604 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3635482 | 0.86 | HPGD (0.76) | HSD17B10HPGDKDM4EALDH1A1ALOX15 | |
| Salsalate SCHEMBL15562 | 0.85 | HSD17B10 (1.00) | HSD17B10HPGDKDM4EALDH1A1ALOX15 | |
| Salsalate SCHEMBL29362887 | 0.85 | HSD17B10 (1.00) | HSD17B10HPGDKDM4EALDH1A1ALOX15 | |
| Salsalate SCHEMBL2025628 | 0.85 | HSD17B10 (1.00) | HSD17B10HPGDKDM4EALDH1A1ALOX15 | |
| SCHEMBL9650827 | 0.85 | HSD17B10 (0.64) | HSD17B10HPGDKDM4EALDH1A1ALOX15 | |
| Salsalate SCHEMBL25177171 | 0.84 | KDM4E (0.96) | HSD17B10HPGDKDM4EALDH1A1ALOX15 | |
| SCHEMBL13826872 | 0.84 | HSD17B10 (0.96) | HSD17B10HPGDKDM4EALDH1A1ALOX15 | |
| Salsalate SCHEMBL9624915 | 0.84 | HSD17B10 (0.96) | HSD17B10HPGDKDM4EALDH1A1ALOX15 | |
| Salsalate SCHEMBL9704557 | 0.84 | HSD17B10 (0.96) | HSD17B10HPGDKDM4EALDH1A1ALOX15 | |
| Salsalate SCHEMBL25260636 | 0.84 | HSD17B10 (0.96) | HSD17B10HPGDKDM4EALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0797453-B1 | COMPOSITION FOR TREATMENT OF MALIGNANT TUMORS AND THEIR METASTASES | CO ENZYME TECHNOLOGY LTD (US) | 2003-03-26 | — | — | EP | claimed |