Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 6/20 | 0.76 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.76 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.69 |
| ▸ | GAA | P10253 | 3/20 | 0.69 |
| ▸ | POLB | P06746 | 1/20 | 0.69 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.66 |
| ▸ | LMNA | P02545 | 4/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | ESR1 | P03372 | 4/20 | 0.54 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10686808 | 0.88 | HSD17B10 (0.71) | HPGDHSD17B10ALDH1A1KDM4EKMT2A | |
| Salsalate SCHEMBL2025628 | 0.86 | HSD17B10 (1.00) | HPGDHSD17B10ALDH1A1KDM4EKMT2A | |
| Salsalate SCHEMBL29362887 | 0.86 | HSD17B10 (1.00) | HPGDHSD17B10ALDH1A1KDM4EKMT2A | |
| SCHEMBL7038760 | 0.86 | HSD17B10 (0.74) | HPGDHSD17B10ALDH1A1KDM4EKMT2A | |
| Salsalate SCHEMBL15562 | 0.86 | HSD17B10 (1.00) | HPGDHSD17B10ALDH1A1KDM4EKMT2A | |
| SCHEMBL10786871 | 0.86 | KMT2A (0.68) | HPGDHSD17B10ALDH1A1KDM4EKMT2A | |
| SCHEMBL28994312 | 0.85 | KMT2A (0.61) | HPGDHSD17B10ALDH1A1KDM4EKMT2A | |
| Salsalate SCHEMBL25260636 | 0.85 | HSD17B10 (0.96) | HPGDHSD17B10ALDH1A1KDM4EKMT2A | |
| SCHEMBL13826872 | 0.85 | HSD17B10 (0.96) | HPGDHSD17B10ALDH1A1KDM4EKMT2A | |
| Salsalate SCHEMBL9624915 | 0.85 | HSD17B10 (0.96) | HPGDHSD17B10ALDH1A1KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8313799-B2 | Adhesive detection methods | HENKEL CORPORATION (US) | 2012-11-20 | — | — | US | claimed |
| US-20100304008-A1 | ADHESIVE DETECTION METHODS | Henkel IP & Holding GmbH (DE) | 2010-12-02 | — | — | US | claimed |
| EP-2150596-A2 | ADHESIVE DETECTION METHODS | Henkel Corporation (US) | 2010-02-10 | — | — | EP | claimed |
| WO-2008153659-A2 | ADHESIVE DETECTION METHODS | HENKEL CORPORATION (US) | 2008-12-18 | — | — | WO | claimed |
| EP-0661591-B1 | Photographic elements containing loaded ultraviolet absorbing polymer latex | EASTMAN KODAK CO (US) | 2000-10-04 | — | — | EP | claimed |
| EP-2582709-B1 | AZOLOPYRIDIN-3-ONE DERIVATIVES AS INHIBITORS OF LIPASES AND PHOSPHOLIPASES | SANOFI SA (FR) | 2018-01-24 | — | — | EP | disclosed |
| EP-2188273-B1 | SUBSTITUTED TETRA HYDRO NAPHTHALINES, METHOD FOR THEIR MANUFACTURE AND THEIR USE AS DRUGS | SANOFI SA (FR) | 2014-10-22 | — | — | EP | disclosed |
| US-20140088077-A1 | NOVEL SUBSTITUTED TETRAHYDRONAPHTHALENES, PROCESS FOR THE PREPARATION THEREOF AND THE USE THEREOF AS MEDICAMENTS | SANOFI (FR) | 2014-03-27 | — | — | US | disclosed |
| US-20140088077-A1 | NOVEL SUBSTITUTED TETRAHYDRONAPHTHALENES, PROCESS FOR THE PREPARATION THEREOF AND THE USE THEREOF AS MEDICAMENTS | SANOFI (FR) | 2014-03-27 | — | — | US | disclosed |
| EP-2220040-B1 | NEW CRYSTALLINE DIPHENYL ACETIDINONE HYDRATE, PHARMACEUTICAL AGENT CONTAINING SAID COMPOUND AND USE THEREOF | SANOFI AVENTIS DEUTSCHLAND (DE) | 2013-01-16 | — | — | EP | disclosed |
| US-8313799-B2 | Adhesive detection methods | HENKEL CORPORATION (US) | 2012-11-20 | — | — | US | disclosed |
| WO-2011157827-A1 | AZOLOPYRIDIN-3-ONE DERIVATIVES AS INHIBITORS OF LIPASES AND PHOSPHOLIPASES | SANOFI (FR) | 2011-12-22 | — | — | WO | disclosed |
| JP-2000212131-A | NEW (METH)ACRYLATE-BASED COMPOUND AND DENTAL POLYMERIZABLE COMPOSITION CONTAINING THE COMPOUND | KURARAY CO LTD | 2000-08-02 | — | — | JP | disclosed |
| EP-0989963-A1 | RADIATION-CURABLE OPTICAL FIBER COATINGS HAVING REDUCED YELLOWING AND FAST CURE SPEED | DSM N.V. (NL) | 2000-04-05 | — | — | EP | disclosed |
| US-5932353-A | NYLON AND POLYURETHANE BLENDS | BASF CORPORATION (US) | 1999-08-03 | — | — | US | disclosed |
| WO-1999034248-A1 | COMPOSITE HOLOGRAPHIC MULTIFOCAL LENS | NOVARTIS AG (CH) | 1999-07-08 | — | — | WO | disclosed |
| WO-1998057902-A1 | RADIATION-CURABLE OPTICAL FIBER COATINGS HAVING REDUCED YELLOWING AND FAST CURE SPEED | DSM N.V. (NL) | 1998-12-23 | — | — | WO | disclosed |
| US-5785916-A | MOLDING POLYURETHANE MATRIX CONTAINING DISPERSED ACRYLIC RUBBER PARTICLES, BENZOTRIAZOLE ULTRAVIOLET STABILIZERS AND PHENOLIC HEAT STABILIZERS, ELASTICITY, HARDNESS | BASF CORPORATION (US) | 1998-07-28 | — | — | US | disclosed |
| EP-0769527-A1 | Thermoplastic polyurethane compositions exhibiting improved UV and heat resistance | BASF CORPORATION (US) | 1997-04-23 | — | — | EP | disclosed |
| US-5286703-A | Having color developing layer and ultraviolet absorbing layer with specific light transmittance; lightfastness | FUJI PHOTO FILM CO., LTD. (JP) | 1994-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140088077-A1 | NOVEL SUBSTITUTED TETRAHYDRONAPHTHALENES, PROCESS FOR THE PREPARATION THEREOF AND THE USE THEREOF AS MEDICAMENTS | DHPS, CYP11B2, CYP11B1 | HPGD 134/4885HSD17B10 587/4885ALDH1A1 863/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.