Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RELA | Q04206 | 4/20 | 0.55 |
| ▸ | PPARA | Q07869 | 4/20 | 0.52 |
| ▸ | CA1 | P00915 | 5/20 | 0.48 |
| ▸ | CA2 | P00918 | 5/20 | 0.48 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | CA7 | P43166 | 2/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | GRIA1 | P42261 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7109328 | 1.00 | RELA (0.55) | RELAPPARACA1CA2CA12 | |
| SCHEMBL7042054 | 1.00 | RELA (0.55) | RELAPPARACA1CA2CA12 | |
| SCHEMBL28469962 | 0.95 | RELA (0.61) | RELAPPARACA1CA2CA12 | |
| SCHEMBL7688181 | 0.95 | RELA (0.61) | RELAPPARACA1CA2CA12 | |
| SCHEMBL11754427 | 0.93 | RELA (0.59) | RELAPPARACA1CA2CA12 | |
| SCHEMBL1753871 | 0.93 | RELA (0.58) | RELAPPARACA1CA2CA12 | |
| SCHEMBL5689484 | 0.90 | CA1 (0.61) | RELAPPARACA1CA2CA12 | |
| SCHEMBL7685651 | 0.86 | RELA (0.71) | RELAPPARACA1CA2CA12 | |
| SCHEMBL7694320 | 0.86 | RELA (0.71) | RELAPPARACA1CA2CA12 | |
| SCHEMBL9609767 | 0.86 | RELA (0.71) | RELAPPARACA1CA2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1292571-A2 | (BIS)SULFONAMIDE DERIVATIVES | ELI LILLY AND COMPANY (US) | 2003-03-19 | — | — | EP | claimed |
| WO-2001094306-A2 | (BIS)SULFONAMIDE DERIVATIVES | ELI LILLY AND COMPANY (US) | 2001-12-13 | — | — | WO | claimed |