Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 2/20 | 0.50 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.50 |
| ▸ | CCR1 | P32246 | 1/20 | 0.47 |
| ▸ | CCR5 | P51681 | 1/20 | 0.47 |
| ▸ | CCR8 | P51685 | 1/20 | 0.47 |
| ▸ | SYK | P43405 | 9/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | JMJD6 | Q6NYC1 | 2/20 | 0.43 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.43 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.43 |
| ▸ | NOS3 | P29474 | 1/20 | 0.43 |
| ▸ | NOS1 | P29475 | 1/20 | 0.43 |
| ▸ | NOS2 | P35228 | 1/20 | 0.43 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21476190 | 0.83 | CYP4F2 (0.47) | CYP4F2CYP4A11SYKPDE3BPDE3A | |
| SCHEMBL30096050 | 0.82 | CCR1 (0.53) | CCR1CCR5CCR8SYK | |
| SCHEMBL17773802 | 0.82 | CCR1 (0.53) | CCR1CCR5CCR8SYK | |
| SCHEMBL16318640 | 0.82 | CYP4F2 (0.55) | CYP4F2CYP4A11SYKPDE3BPDE3A | |
| SCHEMBL10375080 | 0.82 | SYK (0.54) | CYP4F2CYP4A11SYKPDE3BPDE3A | |
| SCHEMBL27224530 | 0.81 | CYP4F2 (0.54) | CYP4F2CYP4A11SYKPDE3BPDE3A | |
| SCHEMBL10375085 | 0.81 | CYP4F2 (0.54) | CYP4F2CYP4A11SYKPDE3BPDE3A | |
| SCHEMBL20103289 | 0.80 | CYP4F2 (0.53) | CYP4F2CYP4A11SYKPDE3BPDE3A | |
| SCHEMBL16318580 | 0.80 | CYP4F2 (0.56) | CYP4F2CYP4A11SYKPDE3BPDE3A | |
| SCHEMBL21476229 | 0.80 | CYP4F2 (0.53) | CYP4F2CYP4A11SYKPDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230100536-A1 | INTERCELLULAR AND INTRACELLULAR PROXIMITY-BASED LABELING COMPOSITIONS AND SYSTEMS | THE TRUSTEES OF PRINCETON UNIVERSITY | 2023-03-30 | — | — | US | disclosed |
| EP-4097116-A1 | INTERCELLULAR AND INTRACELLULAR PROXIMITY-BASED LABELING COMPOSITIONS AND SYSTEMS | The Trustees of Princeton University (US) | 2022-12-07 | — | — | EP | disclosed |
| CN-115397829-A | Compositions and systems for intercellular and intracellular proximity-based labeling | 普林斯顿大学理事会 | 2022-11-25 | — | — | CN | disclosed |
| WO-2003003009-A1 | USE OF METAL-ION CHELATES IN VALIDATING BIOLOGICAL MOLECULES AS DRUG TARGETS IN TEST ANIMAL MODELS | 7TM PHARMA A/S (DK) | 2003-01-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230100536-A1 | INTERCELLULAR AND INTRACELLULAR PROXIMITY-BASED LABELING COMPOSITIONS AND SYSTEMS | FIS1, MCU, TIMM10 | CYP4F2 4253/4885CYP4A11 4879/4885CCR1 3442/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.