SCHEMBL7039554

SCHEMBL7039554

O=C1C(=S)C(Nc2ccccc2)=NN1c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.41
KMT2A Q03164 6/20 0.41
ALDH1A1 P00352 5/20 0.41
MEN1 O00255 4/20 0.41
GAA P10253 2/20 0.41
KDM4E B2RXH2 3/20 0.38
HSP90AA1 P07900 1/20 0.38
CDK4 P11802 1/20 0.38
CCND1 P24385 1/20 0.38
CCND2 P30279 1/20 0.38
CCND3 P30281 1/20 0.38
GRK5 P34947 1/20 0.38
TYRO3 Q06418 1/20 0.38
DYRK1B Q9Y463 1/20 0.38
TDP1 Q9NUW8 4/20 0.37
CYP1A2 P05177 1/20 0.37
CHRM2 P08172 1/20 0.37
CYP3A4 P08684 1/20 0.37
CHRM1 P11229 1/20 0.37
TSHR P16473 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7048797 0.74 ALDH1A1 (0.44) MAPTKMT2AALDH1A1MEN1GAA
SCHEMBL7051110 0.74 MAPT (0.60) MAPTKMT2AALDH1A1MEN1GAA
SCHEMBL6739534 0.65 KMT2A (0.55) MAPTKMT2AALDH1A1MEN1GAA
SCHEMBL6757713 0.64 MEN1 (0.63) MAPTKMT2AALDH1A1MEN1GAA
SCHEMBL11812611 0.62 SMN1; SMN2 (0.39) MAPTKMT2AALDH1A1MEN1GAA
SCHEMBL12291974 0.62 MAPT (0.64) MAPTKMT2AALDH1A1MEN1GAA
SCHEMBL6731372 0.62 KMT2A (0.64) MAPTKMT2AALDH1A1MEN1GAA
SCHEMBL14194451 0.61 KMT2A (0.81) MAPTKMT2AALDH1A1MEN1GAA
SCHEMBL5711337 0.61 MAPT (0.50) MAPTKMT2AALDH1A1MEN1GAA
Diphenylamine SCHEMBL28310372 0.61 HSD17B10 (0.92) MAPTKMT2AALDH1A1MEN1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0740203-B1 Color negative element having improved green record printer compatibility EASTMAN KODAK CO (US) 2003-03-26 EP disclosed
EP-0740203-A2 Color negative element having improved green record printer compatibility EASTMAN KODAK COMPANY (US) 1996-10-30 EP disclosed
US-5563026-A HUE CORRECTING COUPLER EASTMAN KODAK COMPANY (US) 1996-10-08 US disclosed