Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 3/20 | 0.35 |
| ▸ | CA1 | P00915 | 3/20 | 0.35 |
| ▸ | CA2 | P00918 | 3/20 | 0.35 |
| ▸ | CA9 | Q16790 | 3/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.34 |
| ▸ | DHFR | P00374 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | TDP2 | O95551 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1452836 | 0.92 | CA12 (0.33) | ALDH1A1MAPTHPGDMEN1KMT2A | |
| SCHEMBL4622950 | 0.91 | ALDH1A1 (0.36) | ALDH1A1MAPTHPGDMEN1KMT2A | |
| SCHEMBL3996671 | 0.90 | SLC6A4 (0.35) | ALDH1A1MAPTHPGDMEN1KMT2A | |
| SCHEMBL8678964 | 0.88 | ALDH1A1 (0.34) | ALDH1A1MAPTHPGDMEN1KMT2A | |
| SCHEMBL1241803 | 0.87 | ALDH1A1 (0.33) | ALDH1A1MAPTHPGDMEN1KMT2A | |
| SCHEMBL7781565 | 0.87 | CYP1A2 (0.40) | ALDH1A1MAPTHPGDMEN1KMT2A | |
| SCHEMBL4286443 | 0.86 | ALDH1A1 (0.33) | ALDH1A1MAPTHPGDMEN1KMT2A | |
| SCHEMBL7150481 | 0.85 | ALDH1A1 (0.32) | ALDH1A1MAPTHPGDMEN1KMT2A | |
| SCHEMBL1454085 | 0.85 | SLC6A2 (0.33) | ALDH1A1MAPTHPGDMEN1KMT2A | |
| SCHEMBL7038278 | 0.84 | KDM4E (0.41) | ALDH1A1MAPTHPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6620953-B1 | Complexing dimethylbis(2-methyl-4,5-benzoindenyl)silane with transition metal compounds such as 2,4-di-tert-butylphenoxide, zirconium monochloride, to form polymerization catalysts | BASSELL POLYOLEFINE GMBH (DE) | 2003-09-16 | — | — | US | disclosed |
| EP-0985674-B1 | ORGANIC COMPOUNDS CONTAINING SILICON OR GERMANIUM, TRANSITION METAL COMPLEXES, CATALYST FOR ALPHA-OLEFIN POLYMERIZATION, AND PROCESSES FOR PRODUCING ALPHA-OLEFIN POLYMERS | MITSUBISHI CHEM CORP (JP) | 2003-04-23 | — | — | EP | disclosed |
| EP-1133504-B1 | METHOD FOR PRODUCING MONOARYLOXY-ANSA-METALLOCENES | BASELL POLYOLEFINE GMBH (DE) | 2003-03-12 | — | — | EP | disclosed |
| EP-0832866-B1 | Process for the preparation of methylene-bridged biscyclopentadienyl compounds | BASELL POLYOLEFINE GMBH (DE) | 2002-01-09 | — | — | EP | disclosed |
| EP-1134227-A2 | Methylene-bridged biscyclopentadienyl compounds | Basell Polyolefine GmbH (DE) | 2001-09-19 | — | — | EP | disclosed |
| EP-1133504-A1 | METHOD FOR PRODUCING MONOARYLOXY-ANSA-METALLOCENES | Basell Polypropylen GmbH (DE) | 2001-09-19 | — | — | EP | disclosed |
| US-6255508-B1 | COORDINATION CATALYST; ALPHA-OLEFIN POLYMERIZATION CATALYST | TARGOR GMBH (DE) | 2001-07-03 | — | — | US | disclosed |
| WO-2000031091-A1 | METHOD FOR PRODUCING MONOARYLOXY-ANSA-METALLOCENES | BASELL POLYPROPYLEN GMBH (DE) | 2000-06-02 | — | — | WO | disclosed |
| US-5945553-A | Process for preparing a methylene-bridged biscyclopentadienyl compound | TARGOR GMBH (DE) | 1999-08-31 | — | — | US | disclosed |
| EP-0832866-A2 | Process for the preparation of methylene-bridged biscyclopentadienyl compounds | TARGOR GmbH (DE) | 1998-04-01 | — | — | EP | disclosed |