Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 4/20 | 0.59 |
| ▸ | PPARA | Q07869 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 3/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | FLT1 | P17948 | 1/20 | 0.49 |
| ▸ | FLT4 | P35916 | 1/20 | 0.49 |
| ▸ | KDR | P35968 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | CA7 | P43166 | 2/20 | 0.49 |
| ▸ | CA9 | Q16790 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7036191 | 0.88 | PPARG (0.57) | PPARGPPARAALDH1A1RAB9ANPC1 | |
| SCHEMBL7033047 | 0.85 | RAB9A (0.58) | PPARGALDH1A1RAB9ASMN1; SMN2HDAC1 | |
| SCHEMBL7034504 | 0.85 | PPARG (0.54) | PPARGPPARAALDH1A1RAB9ANPC1 | |
| SCHEMBL7040693 | 0.84 | PPARG (0.60) | PPARGPPARAALDH1A1TP53HDAC8 | |
| SCHEMBL7037291 | 0.83 | PPARG (0.52) | PPARGPPARAALDH1A1RAB9ANPC1 | |
| SCHEMBL7038586 | 0.82 | PPARG (0.61) | PPARGPPARAALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL7036241 | 0.81 | PPARG (0.80) | PPARGPPARASMN1; SMN2TP53MAPT | |
| SCHEMBL2889149 | 0.81 | TP53 (0.54) | PPARGPPARAALDH1A1RAB9ANPC1 | |
| SCHEMBL7036249 | 0.80 | PPARG (0.75) | PPARGPPARAALDH1A1RAB9ANPC1 | |
| SCHEMBL7035471 | 0.80 | PPARG (0.49) | PPARGPPARAALDH1A1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030082631-A1 | Compounds modulating PPAR-gamma | BIOVITRUM AB (SE) | 2003-05-01 | — | — | US | disclosed |
| US-20030073862-A1 | Compounds | BIOVITRUM AB (SE) | 2003-04-17 | — | — | US | disclosed |
| WO-2003005025-A1 | METHODS FOR IDENTIFYING COMPOUNDS MODULATING THE ACTIVITY OF PPAR-GAMMA | BIOVITRUM AB (SE) | 2003-01-16 | — | — | WO | disclosed |
| WO-2003004458-A1 | NEW COMPOUNDS | BIOVITRUM AB (SE) | 2003-01-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030082631-A1 | Compounds modulating PPAR-gamma | PPARG, PPARA, PPARD | PPARG 1/4885PPARA 2/4885ALDH1A1 1495/4885 |
| US-20030073862-A1 | Compounds | PPARG, PPARA, PPARD | PPARG 1/4885PPARA 2/4885ALDH1A1 383/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.