SCHEMBL7039692

SCHEMBL7039692

Cc1ccc(CCl)c(Cl)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.48
NPSR1 Q6W5P4 2/20 0.48
LMNA P02545 1/20 0.39
IDO1 P14902 2/20 0.37
CYP1A2 P05177 3/20 0.36
CYP2A6 P11509 2/20 0.36
MAPT P10636 2/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
RAB9A P51151 2/20 0.36
ATM Q13315 1/20 0.36
CYP2C9 P11712 2/20 0.35
MAPK1 P28482 2/20 0.35
CYP2C19 P33261 2/20 0.35
CYP3A4 P08684 1/20 0.35
GABRA1 P14867 2/20 0.35
GABRG2 P18507 2/20 0.35
GABRB3 P28472 2/20 0.35
HPGD P15428 2/20 0.35
GABRB2 P47870 1/20 0.35
MEN1 O00255 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29393025 1.00 KMT2A (0.48) KMT2ANPSR1LMNAIDO1CYP1A2
Trimethylammonium SCHEMBL9757385 0.94 KMT2A (0.44) KMT2ANPSR1LMNAIDO1CYP1A2
SCHEMBL2355598 0.83 TAAR1 (0.40) KMT2ANPSR1LMNAIDO1CYP1A2
SCHEMBL13932525 0.83 AMY1A (0.42) KMT2ANPSR1LMNAIDO1CYP1A2
SCHEMBL8230054 0.81 GRIN2D (0.41) KMT2ANPSR1LMNAIDO1CYP1A2
SCHEMBL16752294 0.81 KMT2A (0.48) KMT2ANPSR1LMNACYP1A2CYP2A6
SCHEMBL9676726 0.80 NPSR1 (0.47) KMT2ANPSR1CYP1A2CYP2A6MAPT
SCHEMBL16998685 0.79 IDO1 (0.35) KMT2ANPSR1LMNAIDO1CYP1A2
SCHEMBL12345506 0.79 IDO1 (0.35) KMT2ANPSR1LMNAIDO1CYP1A2
SCHEMBL5974477 0.79 IDO1 (0.61) KMT2ANPSR1LMNAIDO1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0841347-B1 Synthesis of macrocyclic polymers with group IIA and IIB metal cyclic organometallic initiators BRIDGESTONE CORP (JP) 2003-04-02 EP claimed
EP-0841368-B1 Synthesis of macrocyclic polymers having low hysteresis compounded properties BRIDGESTONE CORP (JP) 2003-03-26 EP claimed
US-5936029-A VULCANIZABLE ELASTOMER; TIRES BRIDGESTONE CORPORATION (JP) 1999-08-10 US claimed
EP-0841347-A1 Synthesis of macrocyclic polymers with group IIA and IIB metal cyclic organometallic initiators Bridgestone Corporation (JP) 1998-05-13 EP claimed
EP-0841356-A1 Synthesis of multiblock polymers using group IIA and IIB metal cyclic organometallic initiators Bridgestone Corporation (JP) 1998-05-13 EP claimed
EP-0841368-A1 Synthesis of macrocyclic polymers having low hysteresis compounded properties Bridgestone Corporation (JP) 1998-05-13 EP claimed
US-5700888-A ANIONIC POLYMERS; VULCANIZABLE ELASTOMERS; CYCLIC ORGANOMETALLIC COMPOUND AS PROMOTERS BRIDGESTONE CORPORATION (JP) 1997-12-23 US claimed
US-5677399-A POLYMERIZATION OF THE MONOMERS BY ADDITION INTO THE INITIATOR RING AT THE BOND BETWEEN THE ATOMS AND ITS TWO ADJUSCENT CARBON ATOMS, METAL ACTS AS A BRIDGE BETWEEN TWO LIVING ENDS OF PROPOGATION CHAIN, AND COUPLING OF LIVING ENDS BRIDGESTONE CORPORATION (JP) 1997-10-14 US claimed
US-5665827-A Synthesis of multiblock polymers using group IIA and IIB metal cyclic organometallic initiators BRIDGESTONE CORPORATION (JP) 1997-09-09 US claimed
US-5302767-A [2.2] paracyclophane and derivatives thereof UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1994-04-12 US claimed
JP-10139804-A None JP disclosed
US-11981801-B2 Polypropylene composition BOREALIS AG (AT) 2024-05-14 US disclosed
US-20230242748-A1 POLYPROPYLENE COMPOSITION BOREALIS AG (AT) 2023-08-03 US disclosed
US-20230242748-A1 POLYPROPYLENE COMPOSITION BOREALIS AG (AT) 2023-08-03 US disclosed
CN-110770264-B Process for preparing heterophasic propylene copolymers 博里利斯股份公司 2022-10-14 CN disclosed
US-5677399-A POLYMERIZATION OF THE MONOMERS BY ADDITION INTO THE INITIATOR RING AT THE BOND BETWEEN THE ATOMS AND ITS TWO ADJUSCENT CARBON ATOMS, METAL ACTS AS A BRIDGE BETWEEN TWO LIVING ENDS OF PROPOGATION CHAIN, AND COUPLING OF LIVING ENDS BRIDGESTONE CORPORATION (JP) 1997-10-14 US disclosed
US-5665827-A Synthesis of multiblock polymers using group IIA and IIB metal cyclic organometallic initiators BRIDGESTONE CORPORATION (JP) 1997-09-09 US disclosed
US-5530139-A BENZO- AND NAPHTHOTHIOPHENE COMPOUNDS; INTERMEDIATES IN AGRICULTURE, FOODS AND MEDICINE, MONOMER FOR ELECTROCONDUCTIVE POLYMER SHOWA DENKO KABUSHIKI KAISHA (JP) 1996-06-25 US disclosed
WO-1990003356-A1 METHOD FOR THE DECOLORIZATION OF CHLORO-XYLENE COMPOSITIONS OCCIDENTAL CHEMICAL CORPORATION (US) 1990-04-05 WO disclosed
US-4364955-A PLANT FUNGI BAYER AKTIENGESELLSCHAFT (DE) 1982-12-21 US disclosed