Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.31 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.31 |
| ▸ | AHR | P35869 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4786951 | 0.75 | CYP3A4 (0.33) | MRGPRX4GPR84CYP3A4MAPK1 | |
| SCHEMBL2089456 | 0.70 | CYP3A4 (0.36) | MRGPRX4GPR84AHRCYP3A4MAPK1 | |
| SCHEMBL11880335 | 0.66 | MRGPRX4 (0.41) | MRGPRX4GPR84AHRCYP3A4MAPK1 | |
| SCHEMBL2097928 | 0.66 | MRGPRX4 (0.45) | MRGPRX4GPR84AHRCYP3A4MAPK1 | |
| SCHEMBL11283671 | 0.65 | CYP3A4 (0.43) | MRGPRX4GPR84AHRCYP3A4MAPK1 | |
| SCHEMBL30715275 | 0.62 | ALDH1A1 (0.46) | CYP3A4MAPK1 | |
| SCHEMBL53547 | 0.62 | ALDH1A1 (0.46) | CYP3A4MAPK1 | |
| SCHEMBL7650059 | 0.62 | CYP3A4 (0.40) | MRGPRX4GPR84AHRCYP3A4MAPK1 | |
| SCHEMBL8767424 | 0.62 | CYP3A4 (0.40) | MRGPRX4GPR84AHRCYP3A4MAPK1 | |
| SCHEMBL27691451 | 0.62 | CYP3A4 (0.40) | MRGPRX4GPR84AHRCYP3A4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030232086-A1 | Gel composition for the topical treatment of rashes, dermatoses and lesions | MCCADDEN MICHAEL E (US) | 2003-12-18 | — | — | US | disclosed |
| US-6656928-B1 | Composition for the topical treatment of rashes, dermatoses and lesions | MCCADDEN MICHAEL E (US) | 2003-12-02 | — | — | US | disclosed |