Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | METTL3 | Q86U44 | 3/20 | 0.36 |
| ▸ | CSF1R | P07333 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | PRKDC | P78527 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA4 | P22748 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | CA5A | P35218 | 2/20 | 0.33 |
| ▸ | CA7 | P43166 | 2/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.33 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.33 |
| ▸ | NCF1 | P14598 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5524115 | 0.84 | NCF1 (0.50) | FGFR1CSF1RPRKDCADAM17NCF1 | |
| SCHEMBL5513306 | 0.74 | NCF1 (0.61) | ADAM17NCF1PKMHSD17B10METAP1 | |
| SCHEMBL5518639 | 0.74 | NCF1 (0.51) | PRKDCMAOBNCF1HSD17B10ALDH1A1 | |
| SCHEMBL5037370 | 0.73 | NCF1 (0.50) | FGFR1METTL3CSF1RPRKDCNCF1 | |
| SCHEMBL5521248 | 0.73 | NCF1 (0.50) | NCF1ALDH1A1 | |
| SCHEMBL5035781 | 0.72 | NCF1 (0.52) | FGFR1METTL3CSF1RCYP3A4PRKDC | |
| Hydrochloric Acid SCHEMBL5040516 | 0.72 | NCF1 (0.49) | FGFR1METTL3CSF1RPRKDCNCF1 | |
| SCHEMBL5514274 | 0.72 | NCF1 (0.49) | NCF1 | |
| SCHEMBL5514944 | 0.72 | NCF1 (0.46) | MAOBNCF1 | |
| Hydrochloric Acid SCHEMBL5042681 | 0.72 | NCF1 (0.51) | FGFR1METTL3CSF1RCYP3A4PRKDC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1432421-A1 | QUINOLINE DERIVATIVES AS NEUROPEPTIDE Y ANTAGONISTS | F. Hoffmann-La Roche AG (CH) | 2004-06-30 | — | — | EP | disclosed |
| WO-2003028726-A1 | QUINOLINE DERIVATIVES AS NEUROPEPTIDE Y ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2003-04-10 | — | — | WO | disclosed |