Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.69 |
| ▸ | RAB9A | P51151 | 6/20 | 0.69 |
| ▸ | GAA | P10253 | 5/20 | 0.69 |
| ▸ | NPC1 | O15118 | 5/20 | 0.69 |
| ▸ | CASP3 | P42574 | 1/20 | 0.69 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.69 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.69 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.69 |
| ▸ | ALOX5 | P09917 | 6/20 | 0.63 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.62 |
| ▸ | MAPT | P10636 | 6/20 | 0.62 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.62 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.62 |
| ▸ | RELA | Q04206 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.62 |
| ▸ | AMY1A | P0DUB6 | 2/20 | 0.56 |
| ▸ | VCP | P55072 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12297855 | 0.90 | PTGS2 (0.68) | MEN1KMT2ARAB9AGAANPC1 | |
| SCHEMBL12297709 | 0.89 | MEN1 (0.62) | MEN1KMT2ARAB9AGAANPC1 | |
| SCHEMBL12298062 | 0.88 | MEN1 (0.67) | MEN1KMT2ARAB9AGAANPC1 | |
| SCHEMBL12297952 | 0.87 | MEN1 (0.66) | MEN1KMT2ARAB9AGAANPC1 | |
| SCHEMBL12297421 | 0.87 | MEN1 (0.66) | MEN1KMT2ARAB9AGAANPC1 | |
| SCHEMBL12297663 | 0.87 | MEN1 (0.66) | MEN1KMT2ARAB9AGAANPC1 | |
| SCHEMBL12297318 | 0.87 | GAA (0.66) | MEN1KMT2ARAB9AGAANPC1 | |
| SCHEMBL12298275 | 0.87 | MAPT (0.72) | MEN1KMT2ARAB9AGAANPC1 | |
| SCHEMBL12297355 | 0.87 | MEN1 (0.62) | MEN1KMT2ARAB9AGAANPC1 | |
| SCHEMBL12298202 | 0.86 | CYP1A2 (0.61) | MEN1KMT2ARAB9AGAANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030158199-A1 | Novel compounds for inhibition of Tie-2 | KYLIX, B.V. (NL) | 2003-08-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030158199-A1 | Novel compounds for inhibition of Tie-2 | TIE1, TEK, KDR | MEN1 839/4885KMT2A 499/4885RAB9A 3641/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.