Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 18/20 | 0.68 |
| ▸ | PPARA | Q07869 | 16/20 | 0.61 |
| ▸ | PPARD | Q03181 | 5/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7038651 | 0.92 | PPARG (0.57) | PPARGPPARAPPARD | |
| SCHEMBL6738244 | 0.91 | PPARG (0.69) | PPARGPPARAPPARD | |
| SCHEMBL7034640 | 0.91 | PPARG (0.56) | PPARGPPARAPPARD | |
| SCHEMBL6737303 | 0.85 | PPARG (0.66) | PPARGPPARAPPARD | |
| SCHEMBL7035857 | 0.84 | PPARG (0.75) | PPARGPPARAPPARD | |
| SCHEMBL6735691 | 0.83 | PPARG (0.75) | PPARGPPARAPPARD | |
| SCHEMBL7529707 | 0.81 | PPARG (0.78) | PPARGPPARAPPARD | |
| SCHEMBL7523772 | 0.81 | PPARG (1.00) | PPARGPPARAPPARD | |
| SCHEMBL7528218 | 0.80 | PPARG (0.92) | PPARGPPARAPPARD | |
| SCHEMBL6956717 | 0.79 | PPARG (0.66) | PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003006022-A1 | TETRAHYDROQUINOLINE DERIVATIVES AND THEIR USE IN MEDICINE, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DR. REDDY'S LABORATORIES LTD. (IN) | 2003-01-23 | — | — | WO | claimed |
| WO-2003006022-A1 | TETRAHYDROQUINOLINE DERIVATIVES AND THEIR USE IN MEDICINE, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DR. REDDY'S LABORATORIES LTD. (IN) | 2003-01-23 | — | — | WO | disclosed |