Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 19/20 | 0.56 |
| ▸ | PPARA | Q07869 | 17/20 | 0.50 |
| ▸ | PPARD | Q03181 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7038651 | 0.94 | PPARG (0.57) | PPARGPPARAPPARD | |
| SCHEMBL7040118 | 0.91 | PPARG (0.68) | PPARGPPARAPPARD | |
| SCHEMBL7107208 | 0.84 | PPARG (0.62) | PPARGPPARAPPARD | |
| SCHEMBL6738244 | 0.82 | PPARG (0.69) | PPARGPPARAPPARD | |
| SCHEMBL6949400 | 0.80 | PPARG (0.54) | PPARGPPARAPPARD | |
| SCHEMBL5107151 | 0.78 | PPARG (0.57) | PPARGPPARAPPARD | |
| SCHEMBL5100503 | 0.78 | LMNA (0.54) | PPARGPPARAPPARD | |
| SCHEMBL7106185 | 0.78 | PPARG (0.63) | PPARGPPARAPPARD | |
| SCHEMBL5101768 | 0.78 | PPARG (0.62) | PPARGPPARAPPARD | |
| SCHEMBL6737303 | 0.76 | PPARG (0.66) | PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003006022-A1 | TETRAHYDROQUINOLINE DERIVATIVES AND THEIR USE IN MEDICINE, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DR. REDDY'S LABORATORIES LTD. (IN) | 2003-01-23 | — | — | WO | claimed |
| WO-2003006022-A1 | TETRAHYDROQUINOLINE DERIVATIVES AND THEIR USE IN MEDICINE, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DR. REDDY'S LABORATORIES LTD. (IN) | 2003-01-23 | — | — | WO | disclosed |