Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.31 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.31 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.31 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.31 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28131148 | 0.89 | TSHR (0.33) | TSHRDNM1LPAR1LPAR3ADRB2 | |
| SCHEMBL8143953 | 0.85 | TSHR (0.41) | TSHRLPAR1LPAR3ADRB2ADRB1 | |
| SCHEMBL28534846 | 0.84 | TSHR (0.39) | TSHRDNM1LPAR1LPAR3ADRB2 | |
| SCHEMBL11760550 | 0.84 | THRB (0.40) | — | |
| SCHEMBL615986 | 0.84 | TSHR (0.30) | TSHR | |
| SCHEMBL8616123 | 0.82 | TSHR (0.52) | TSHRLPAR1LPAR3LPAR2 | |
| SCHEMBL1984877 | 0.82 | CYP3A4 (0.40) | DNM1LPAR1LPAR3ADRB2ADRB1 | |
| SCHEMBL9502490 | 0.82 | TSHR (0.42) | TSHRDNM1LPAR1LPAR3ADRB2 | |
| SCHEMBL28458040 | 0.82 | USP2 (0.48) | DNM1LPAR1LPAR3LPAR2 | |
| SCHEMBL28357447 | 0.81 | TSHR (0.43) | TSHRLPAR1LPAR3LPAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0470040-B1 | Process for the preparation of a rubber having polymer bound functionality | GOODYEAR TIRE & RUBBER (US) | 1996-09-11 | — | — | EP | claimed |
| EP-0470042-B1 | Process for the preparation of a masterbatch rubber having polymer bound functionality | GOODYEAR TIRE & RUBBER (US) | 1996-05-08 | — | — | EP | claimed |
| WO-2003006255-A1 | PRINTING FACE FORMULARY | REEVES BROTHERS, INC. (US) | 2003-01-23 | — | — | WO | disclosed |