Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 4/20 | 0.69 |
| ▸ | GSK3B | P49841 | 2/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | TTR | P02766 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | F2 | P00734 | 1/20 | 0.30 |
| ▸ | ACLY | P53396 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL788050 | 0.82 | DAO (1.00) | DAOGSK3BTTRMEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8935127 | 0.80 | DAO (0.95) | DAOGSK3BCYP2D6SLC6A2SLC6A4 | |
| SCHEMBL7044853 | 0.79 | DAO (0.44) | DAOGSK3BMEN1KMT2AGPR35 | |
| SCHEMBL5009880 | 0.76 | DAO (0.65) | DAOGSK3BCYP2D6SLC6A2SLC6A4 | |
| SCHEMBL2987123 | 0.76 | DAO (0.65) | DAOGSK3BCYP2D6SLC6A2SLC6A4 | |
| SCHEMBL6788530 | 0.72 | GSK3B (1.00) | DAOGSK3BCYP2D6SLC6A2SLC6A4 | |
| SCHEMBL1182967 | 0.72 | DAO (0.50) | DAOGSK3BCYP2D6SLC6A2SLC6A4 | |
| SCHEMBL31593316 | 0.71 | GSK3B (0.69) | DAOGSK3BCYP2D6SLC6A2SLC6A4 | |
| SCHEMBL27534655 | 0.71 | GSK3B (0.69) | DAOGSK3BCYP2D6SLC6A2SLC6A4 | |
| SCHEMBL21612137 | 0.70 | DAO (0.56) | DAOGSK3BPOLBMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1980710-B | Substituted azepine derivatives as serotonin receptor modulators | ATHERSYS INC | 2013-06-12 | — | — | CN | disclosed |
| CN-1980710-A | Substituted azepine derivatives as serotonin receptor modulators | ATHERSYS INC (US) | 2007-06-13 | — | — | CN | disclosed |
| US-6613786-B2 | Treating urinary incontinence, asthma, irritable bowel syndrome or male erectile dysfunction | BRISTOL-MYERS SQUIBB COMPANY | 2003-09-02 | — | — | US | disclosed |
| US-20030144333-A1 | Thiophenyl triazol-3-one derivatives as smooth muscle relaxants | HEWAWASAM PIYASENA (US) | 2003-07-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030144333-A1 | Thiophenyl triazol-3-one derivatives as smooth muscle relaxants | PDE3A, ADRB2, ADRB3 | DAO 3738/4885GSK3B 3398/4885CYP2D6 599/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.