Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.38 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7042816 | 0.96 | ABCB1 (0.44) | ALDH1A1ABCB1MEN1KMT2ANPY5R | |
| SCHEMBL7042722 | 0.84 | ALDH1A1 (0.41) | ALDH1A1ABCB1MEN1KMT2ANPY5R | |
| SCHEMBL7037082 | 0.84 | NPY5R (0.39) | ALDH1A1MEN1KMT2ANPY5RTSHR | |
| SCHEMBL7176602 | 0.83 | ALDH1A1 (0.40) | ALDH1A1ABCB1MEN1KMT2ATSHR | |
| SCHEMBL7040475 | 0.83 | ALDH1A1 (0.40) | ALDH1A1ABCB1MEN1KMT2ATSHR | |
| SCHEMBL7176605 | 0.82 | ABCB1 (0.44) | ALDH1A1ABCB1MEN1KMT2ATSHR | |
| SCHEMBL7039648 | 0.81 | ABCB1 (0.43) | ALDH1A1ABCB1MEN1KMT2ANPY5R | |
| SCHEMBL7039495 | 0.81 | ALDH1A1 (0.40) | ALDH1A1ABCB1MEN1KMT2ATSHR | |
| SCHEMBL7044393 | 0.81 | ALDH1A1 (0.44) | ALDH1A1ABCB1MEN1KMT2ATSHR | |
| SCHEMBL7251318 | 0.80 | BCHE (0.48) | ALDH1A1ABCB1MEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1292564-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-03-19 | — | — | EP | disclosed |
| WO-2001062705-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-08-30 | — | — | WO | disclosed |