Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | CTSD | P07339 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13753116 | 0.79 | CTSD (0.64) | LMNACTSDALDH1A1MEN1KMT2A | |
| SCHEMBL9492867 | 0.78 | CTSD (0.66) | LMNACTSDALDH1A1MEN1KMT2A | |
| SCHEMBL28738502 | 0.78 | CTSD (0.66) | LMNACTSDALDH1A1MEN1KMT2A | |
| SCHEMBL11554301 | 0.77 | NPC1 (0.65) | LMNAALDH1A1HPGDHTTTMEM97 | |
| SCHEMBL4960015 | 0.77 | HTT (0.69) | LMNACTSDALDH1A1MEN1KMT2A | |
| SCHEMBL7425750 | 0.76 | CTSD (0.64) | LMNACTSDALDH1A1MEN1KMT2A | |
| SCHEMBL11719219 | 0.76 | CTSD (0.64) | LMNACTSDALDH1A1MEN1KMT2A | |
| SCHEMBL22163884 | 0.76 | CTSD (0.69) | LMNACTSDALDH1A1MEN1KMT2A | |
| SCHEMBL7038868 | 0.76 | TMEM97 (0.70) | LMNAALDH1A1MEN1KMT2AHTT | |
| SCHEMBL13753006 | 0.76 | CTSD (0.68) | LMNACTSDALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1052248-B1 | Process for the preparation of aqueous solutions of diazonium salts | CLARIANT GMBH (DE) | 2003-03-19 | — | — | EP | disclosed |
| US-6207809-B1 | CATALYTIC HYDROGENATION USING THE CORRESPONDING NITRO COMPOUND | CLARIANT GMBH (DE) | 2001-03-27 | — | — | US | disclosed |
| EP-1052248-A1 | Process for the preparation of aqueous solutions of diazonium salts | Clariant GmbH (DE) | 2000-11-15 | — | — | EP | disclosed |