SCHEMBL7041801

SCHEMBL7041801

CCn1c(C(=O)OC)nc(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1Cl

nearest known ligand 0.56

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 14/20 0.56
DPP4 P27487 1/20 0.46
OPRL1 P41146 1/20 0.44
ALPL P05186 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7044616 0.92 CNR1 (0.66) CNR1OPRL1
SCHEMBL6552035 0.92 CNR1 (0.56) CNR1DPP4OPRL1
SCHEMBL7045699 0.82 CNR1 (0.62) CNR1DPP4OPRL1
SCHEMBL4080145 0.82 CNR1 (0.52) CNR1DPP4
SCHEMBL4085247 0.76 CNR1 (0.57) CNR1DPP4
SCHEMBL4075955 0.73 CNR1 (0.66) CNR1
SCHEMBL4075880 0.73 CNR1 (0.77) CNR1OPRL1
SCHEMBL4079594 0.73 CNR1 (0.77) CNR1
SCHEMBL4076187 0.72 CNR1 (0.86) CNR1OPRL1
SCHEMBL4076008 0.72 CNR1 (1.00) CNR1OPRL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2003007887-A2 SUBSTITUTED IMIDAZOLES AS CANNABINOID RECEPTOR MODULATORS MERCK & CO., INC. (US) 2003-01-30 WO disclosed