Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 13/20 | 0.56 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.45 |
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7041801 | 0.92 | CNR1 (0.56) | CNR1OPRL1DPP4 | |
| SCHEMBL7044616 | 0.91 | CNR1 (0.66) | CNR1OPRL1 | |
| SCHEMBL4080145 | 0.90 | CNR1 (0.52) | CNR1DPP4 | |
| SCHEMBL7045699 | 0.81 | CNR1 (0.62) | CNR1OPRL1DPP4 | |
| SCHEMBL4079594 | 0.81 | CNR1 (0.77) | CNR1 | |
| SCHEMBL4075955 | 0.81 | CNR1 (0.66) | CNR1 | |
| SCHEMBL4076187 | 0.80 | CNR1 (0.86) | CNR1OPRL1 | |
| SCHEMBL7043322 | 0.78 | CNR1 (0.61) | CNR1OPRL1 | |
| SCHEMBL4080087 | 0.78 | CNR1 (0.59) | CNR1OPRL1DPP4 | |
| SCHEMBL7044993 | 0.76 | CNR1 (0.44) | CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003007887-A2 | SUBSTITUTED IMIDAZOLES AS CANNABINOID RECEPTOR MODULATORS | MERCK & CO., INC. (US) | 2003-01-30 | — | — | WO | claimed |
| EP-1482794-A1 | METHOD OF TREATMENT OR PREVENTION OF OBESITY | Merck & Co., Inc. (US) | 2004-12-08 | — | — | EP | disclosed |
| WO-2003075660-A1 | METHOD OF TREATMENT OR PREVENTION OF OBESITY | MERCK & CO., INC. (US) | 2003-09-18 | — | — | WO | disclosed |
| WO-2003007887-A2 | SUBSTITUTED IMIDAZOLES AS CANNABINOID RECEPTOR MODULATORS | MERCK & CO., INC. (US) | 2003-01-30 | — | — | WO | disclosed |