Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPBWR1 | P48145 | 10/20 | 0.61 |
| ▸ | NPC1 | O15118 | 5/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | RAB9A | P51151 | 5/20 | 0.56 |
| ▸ | HTT | P42858 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.56 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | RELA | Q04206 | 3/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | STAT1 | P42224 | 1/20 | 0.56 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.56 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.56 |
| ▸ | MMP2 | P08253 | 2/20 | 0.55 |
| ▸ | MMP9 | P14780 | 2/20 | 0.55 |
| ▸ | MMP8 | P22894 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7041761 | 0.92 | NPBWR1 (0.50) | NPBWR1NPC1MAPTRAB9AHTT | |
| SCHEMBL5219206 | 0.88 | NPBWR1 (0.77) | NPBWR1NPC1MAPTRAB9AHTT | |
| SCHEMBL7040027 | 0.88 | CHEK2 (0.62) | NPBWR1NPC1MAPTRAB9AHTT | |
| SCHEMBL19995192 | 0.82 | NPBWR1 (0.69) | NPBWR1NPC1MAPTRAB9AHTT | |
| SCHEMBL7038689 | 0.81 | KDM4E (0.75) | NPC1MAPTRAB9ASMN1; SMN2MEN1 | |
| SCHEMBL3183363 | 0.80 | NPBWR1 (0.63) | NPBWR1NPC1MAPTRAB9AHTT | |
| SCHEMBL14599560 | 0.80 | PLAU (0.63) | NPBWR1NPC1MAPTRAB9AHTT | |
| SCHEMBL7034855 | 0.79 | CHEK2 (0.54) | NPBWR1NPC1MAPTRAB9AHTT | |
| SCHEMBL14583010 | 0.79 | CHEK2 (0.50) | NPBWR1NPC1MAPTRAB9AHTT | |
| SCHEMBL14400748 | 0.79 | CHEK2 (0.50) | NPBWR1NPC1MAPTRAB9AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030104473-A1 | Common ligand mimics: benzimidazoles | TRIAD THERAPEUTICS, INC. | 2003-06-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030104473-A1 | Common ligand mimics: benzimidazoles | BID, LIFR, FGFR3 | NPBWR1 876/4885NPC1 3867/4885MAPT 4471/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.