Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 13/20 | 0.70 |
| ▸ | ADRB1 | P08588 | 13/20 | 0.70 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7044330 | 0.88 | ADRB3 (0.71) | ADRB3ADRB1ADRB2CYP2D6MEN1 | |
| SCHEMBL6478914 | 0.86 | ADRB3 (0.71) | ADRB3ADRB1ADRB2CYP2D6MEN1 | |
| SCHEMBL6478911 | 0.86 | ADRB3 (0.71) | ADRB3ADRB1ADRB2CYP2D6MEN1 | |
| SCHEMBL6538997 | 0.86 | ADRB3 (0.82) | ADRB3ADRB1ADRB2CYP2D6MEN1 | |
| SCHEMBL7042706 | 0.85 | ADRB1 (0.71) | ADRB3ADRB1ADRB2CYP2D6MEN1 | |
| SCHEMBL7039822 | 0.85 | ADRB3 (0.74) | ADRB3ADRB1ADRB2CYP2D6MEN1 | |
| SCHEMBL7041978 | 0.85 | ADRB3 (0.74) | ADRB3ADRB1ADRB2CYP2D6TDP1 | |
| SCHEMBL7044140 | 0.85 | ADRB3 (0.73) | ADRB3ADRB1ADRB2CYP2D6MEN1 | |
| SCHEMBL7041021 | 0.83 | ADRB3 (0.71) | ADRB3ADRB1ADRB2CYP2D6MEN1 | |
| SCHEMBL7044333 | 0.83 | ADRB3 (0.71) | ADRB3ADRB1ADRB2CYP2D6MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1292564-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-03-19 | — | — | EP | disclosed |
| WO-2001062705-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-08-30 | — | — | WO | disclosed |