Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7040583 | 0.93 | TP53 (0.37) | TP53MAPTHPGDTSHRMEN1 | |
| SCHEMBL976037 | 0.91 | TP53 (0.34) | TP53MAPTHPGDTSHRMEN1 | |
| SCHEMBL976618 | 0.90 | TP53 (0.34) | TP53MAPTHPGDTSHRMEN1 | |
| SCHEMBL977986 | 0.89 | TP53 (0.33) | TP53MAPTHPGDTSHRMEN1 | |
| SCHEMBL976788 | 0.89 | TP53 (0.33) | TP53MAPTHPGDTSHRMEN1 | |
| SCHEMBL977288 | 0.89 | TP53 (0.33) | TP53MAPTHPGDTSHRMEN1 | |
| SCHEMBL12922182 | 0.88 | TP53 (0.35) | TP53MAPTHPGDTSHRMEN1 | |
| SCHEMBL976049 | 0.88 | TP53 (0.36) | TP53MAPTHPGDTSHRMEN1 | |
| SCHEMBL977642 | 0.88 | TP53 (0.36) | TP53MAPTHPGDTSHRMEN1 | |
| SCHEMBL977745 | 0.87 | TP53 (0.36) | TP53MAPTHPGDTSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1341763-B1 | N-ALKOXY-4,4-DIOXY-POLYALKYL-PIPERIDINE COMPOUNDS, WITH GLYCIDYL OR ALKYLCARBONYL GROUPS AS FUNCTIONAL INITIATORS FOR CONTROLLED RADICAL POLYMERIZATION | CIBA SC HOLDING AG (CH) | 2004-06-16 | — | — | EP | claimed |