SCHEMBL976049

SCHEMBL976049

CCC1(CC)CC2(CC(C)(C)N1OC(C)c1ccc(OCC3CO3)cc1)OCCO2

nearest known ligand 0.36

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TP53 P04637 3/20 0.36
TSHR P16473 3/20 0.36
ALDH1A1 P00352 3/20 0.36
MAPT P10636 2/20 0.36
HPGD P15428 2/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
HIF1A Q16665 2/20 0.36
CYP1A2 P05177 1/20 0.36
PPARG P37231 1/20 0.36
TDP1 Q9NUW8 1/20 0.34
PKM P14618 2/20 0.34
LMNA P02545 1/20 0.34
GAA P10253 1/20 0.34
GRM2 Q14416 1/20 0.33
HRH3 Q9Y5N1 2/20 0.32
CYP3A4 P08684 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL977745 0.97 TP53 (0.36) TP53TSHRALDH1A1MAPTHPGD
SCHEMBL977642 0.94 TP53 (0.36) TP53TSHRALDH1A1MAPTHPGD
SCHEMBL12922168 0.92 TP53 (0.35) TP53TSHRALDH1A1MAPTHPGD
SCHEMBL12922182 0.92 TP53 (0.35) TP53TSHRALDH1A1MAPTHPGD
SCHEMBL974403 0.92 TP53 (0.35) TP53TSHRALDH1A1MAPTHPGD
SCHEMBL974715 0.92 ALDH1A1 (0.40) TP53TSHRALDH1A1MAPTHPGD
SCHEMBL976517 0.92 TP53 (0.34) TP53TSHRALDH1A1MAPTHPGD
SCHEMBL975037 0.92 TP53 (0.34) TP53TSHRALDH1A1MAPTHPGD
SCHEMBL7041222 0.91 TP53 (0.34) TP53TSHRALDH1A1MAPTHPGD
SCHEMBL976037 0.90 TP53 (0.34) TP53TSHRALDH1A1MAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070173570-A1 N-alkoxy-4, 4-dioxy-polyalkyl-piperidine compounds, with glycidyl or alkylcarbonyl groups as functional initiators for controlled radical polymerization FUSO FRANCESCO 2007-07-26 US claimed
US-7235663-B2 N-alkoxy-4,4-dioxy-polyalkyl-piperidines as radical polymerization inhibitors CIBA SPECIALTY CHEMICALS CORP. (US) 2007-06-26 US claimed
EP-1341763-B1 N-ALKOXY-4,4-DIOXY-POLYALKYL-PIPERIDINE COMPOUNDS, WITH GLYCIDYL OR ALKYLCARBONYL GROUPS AS FUNCTIONAL INITIATORS FOR CONTROLLED RADICAL POLYMERIZATION CIBA SC HOLDING AG (CH) 2004-06-16 EP claimed
US-20040049043-A1 N-alkoxy-4,4-dioxy-polyalkyl-piperidine compounds, with glycidyl or alkylcarbonyl groups as functional initiators for controlled radical polymerization CIBA SPECIALTY CHEMICALS CORP. 2004-03-11 US claimed
EP-1341763-A2 N-ALKOXY-4,4-DIOXY-POLYALKYL-PIPERIDINE COMPOUNDS, WITH GLYCIDYL OR ALKYLCARBONYL GROUPS AS FUNCTIONAL INITIATORS FOR CONTROLLED RADICAL POLYMERIZATION Ciba SC Holding AG (CH) 2003-09-10 EP claimed
WO-2002048109-A2 N-ALKOXY-4,4-DIOXY-POLYALKYL-PIPERIDINES AS RADICAL POLYMERIZATION INITIATORS CIBA SPECIALTY CHEMICLAS HOLDING INC. (CH) 2002-06-20 WO claimed
US-8544658-B2 Functionalized thin film polyamide membranes POLYMERS CRC LIMITED (AU) 2013-10-01 US disclosed
US-8544658-B2 Functionalized thin film polyamide membranes POLYMERS CRC LIMITED (AU) 2013-10-01 US disclosed
US-8544658-B2 Functionalized thin film polyamide membranes POLYMERS CRC LIMITED (AU) 2013-10-01 US disclosed
EP-2313184-B1 FUNCTIONALIZED THIN FILM POLYAMIDE MEMBRANES POLYMERS CRC LTD (AU) 2012-10-10 EP disclosed
EP-2313184-B1 FUNCTIONALIZED THIN FILM POLYAMIDE MEMBRANES POLYMERS CRC LTD (AU) 2012-10-10 EP disclosed
US-20110189469-A1 FUNCTIONALIZED THIN FILM POLYAMIDE MEMBRANES POLYMERS CRC LIMITED (AU) 2011-08-04 US disclosed
US-20110189469-A1 FUNCTIONALIZED THIN FILM POLYAMIDE MEMBRANES POLYMERS CRC LIMITED (AU) 2011-08-04 US disclosed
US-6967228-B2 Stable free radical polymers FIRESTONE POLYMERS, LLC (US) 2005-11-22 US disclosed
US-20040220345-A1 Stable free radical polymers FIRESTONE POLYMERS, LLC 2004-11-04 US disclosed
US-20040220344-A1 Stable free radical polymers FIRESTONE POLYMERS, LLC. 2004-11-04 US disclosed
EP-1473312-A2 Stable free radical polymers Firestone Polymers, LLC (US) 2004-11-03 EP disclosed
EP-1341763-B1 N-ALKOXY-4,4-DIOXY-POLYALKYL-PIPERIDINE COMPOUNDS, WITH GLYCIDYL OR ALKYLCARBONYL GROUPS AS FUNCTIONAL INITIATORS FOR CONTROLLED RADICAL POLYMERIZATION CIBA SC HOLDING AG (CH) 2004-06-16 EP disclosed
EP-1341763-A2 N-ALKOXY-4,4-DIOXY-POLYALKYL-PIPERIDINE COMPOUNDS, WITH GLYCIDYL OR ALKYLCARBONYL GROUPS AS FUNCTIONAL INITIATORS FOR CONTROLLED RADICAL POLYMERIZATION Ciba SC Holding AG (CH) 2003-09-10 EP disclosed
WO-2002048109-A2 N-ALKOXY-4,4-DIOXY-POLYALKYL-PIPERIDINES AS RADICAL POLYMERIZATION INITIATORS CIBA SPECIALTY CHEMICLAS HOLDING INC. (CH) 2002-06-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070173570-A1 N-alkoxy-4, 4-dioxy-polyalkyl-piperidine compounds, with glycidyl or alkylcarbonyl groups as functional initiators for controlled radical polymerization PTGER4, ALKBH3, PIGO TP53 4722/4885TSHR 4817/4885ALDH1A1 737/4885
US-20040049043-A1 N-alkoxy-4,4-dioxy-polyalkyl-piperidine compounds, with glycidyl or alkylcarbonyl groups as functional initiators for controlled radical polymerization PAOX, ALKBH3, PTGER4 TP53 4311/4885TSHR 4856/4885ALDH1A1 1472/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.