SCHEMBL704247

SCHEMBL704247

C=C(C(=O)O)C1CC1.C=C(CC)C(=O)OCCCC

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.42
ALDH1A1 P00352 1/20 0.38
HPGD P15428 1/20 0.38
ATM Q13315 1/20 0.36
HCAR2 Q8TDS4 3/20 0.36
NAAA Q02083 1/20 0.35
CHRM2 P08172 3/20 0.32
CHRM1 P11229 3/20 0.32
CHRM4 P08173 2/20 0.32
CHRM5 P08912 2/20 0.32
CHRM3 P20309 2/20 0.32
POLB P06746 2/20 0.32
LMNA P02545 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
TDP1 Q9NUW8 2/20 0.32
L3MBTL1 Q9Y468 2/20 0.32
CCNE2 O96020 1/20 0.32
CCNE1 P24864 1/20 0.32
CDK2 P24941 1/20 0.32
APEX1 P27695 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL48561 0.88 TSHR (0.58) TSHRALDH1A1HPGDATMHCAR2
SCHEMBL14916019 0.84 TSHR (0.50) TSHRALDH1A1HPGDATMHCAR2
SCHEMBL375032 0.83 TSHR (0.57) TSHRALDH1A1HPGDATMHCAR2
SCHEMBL10336636 0.82 TSHR (0.69) TSHRALDH1A1HCAR2NAAAPOLB
SCHEMBL17181039 0.82 TSHR (0.69) TSHRALDH1A1HCAR2NAAAPOLB
Methacrylic Acid SCHEMBL28317308 0.82 TSHR (0.58) TSHRALDH1A1HPGDATMHCAR2
SCHEMBL48291 0.81 TSHR (0.65) TSHRALDH1A1HPGDATMHCAR2
SCHEMBL374970 0.78 TSHR (0.66) TSHRALDH1A1HPGDATMHCAR2
Acrylic Acid SCHEMBL28214938 0.78 TSHR (0.55) TSHRALDH1A1HPGDATMHCAR2
SCHEMBL7868573 0.78 TSHR (0.61) TSHRALDH1A1HCAR2NAAALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8124681-B2 Golf ball with high moisture barrier properties ACUSHNET COMPANY (US) 2012-02-28 US disclosed
US-20100151969-A1 GOLF BALL WITH HIGH MOISTURE BARRIER PROPERTIES JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2010-06-17 US disclosed
US-7695381-B1 Golf ball with high moisture barrier properties ACUSHNET COMPANY (US) 2010-04-13 US disclosed