Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | CASP7 | P55210 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.43 |
| ▸ | CHUK | O15111 | 1/20 | 0.43 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
| ▸ | PRKCG | P05129 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7750781 | 1.00 | TSHR (0.50) | TSHRGAAALDH1A1MAPTKDM4E | |
| SCHEMBL7747651 | 1.00 | TSHR (0.50) | TSHRGAAALDH1A1MAPTKDM4E | |
| SCHEMBL7748209 | 1.00 | TSHR (0.50) | TSHRGAAALDH1A1MAPTKDM4E | |
| SCHEMBL7045171 | 0.92 | TSHR (0.57) | TSHRGAAALDH1A1MAPTKDM4E | |
| SCHEMBL1608893 | 0.92 | TSHR (0.57) | TSHRGAAALDH1A1MAPTKDM4E | |
| SCHEMBL9168790 | 0.92 | TSHR (0.57) | TSHRGAAALDH1A1MAPTKDM4E | |
| SCHEMBL17817108 | 0.92 | TSHR (0.57) | TSHRGAAALDH1A1MAPTKDM4E | |
| SCHEMBL3278460 | 0.92 | TSHR (0.57) | TSHRGAAALDH1A1MAPTKDM4E | |
| SCHEMBL7045133 | 0.92 | TSHR (0.57) | TSHRGAAALDH1A1MAPTKDM4E | |
| SCHEMBL7043129 | 0.92 | TSHR (0.57) | TSHRGAAALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6323163-B1 | PERFLUOROPOLYOXYALKYLENE CHAIN HAVING AVERAGE MOLECULAR WEIGHT OF 800 OR MORE, CONTAINING CYCLIC POLYETHER GROUP HAVING AT LEAST 4 OXYGEN ATOMS, ALSO HAVING AMIDE, SULFONAMIDE, ETHER OR ESTER LINKAGE BETWEEN CHAIN AND CYCLIC GROUP | HITACHI, LTD. (JP) | 2001-11-27 | — | — | US | disclosed |