Fluoride

Fluoride

SCHEMBL704319

F.F.F.[SiH3]c1ccccc1

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.40
TSHR P16473 6/20 0.37
DPP4 P27487 2/20 0.37
F2 P00734 1/20 0.37
CA1 P00915 2/20 0.35
CA2 P00918 2/20 0.35
CA9 Q16790 2/20 0.35
TDP1 Q9NUW8 2/20 0.35
ALOX12 P18054 2/20 0.35
CA12 O43570 1/20 0.35
GLA P06280 1/20 0.35
CA3 P07451 1/20 0.35
CA4 P22748 1/20 0.35
CA14 Q9ULX7 1/20 0.35
LMNA P02545 1/20 0.35
ACHE P22303 1/20 0.35
CA7 P43166 1/20 0.35
HIF1A Q16665 1/20 0.35
CYP2A6 P11509 1/20 0.33
MAPT P10636 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluoride SCHEMBL27930956 1.00
Fluoride SCHEMBL8209198 0.96 ALDH1A1 (0.38) ALDH1A1TSHRDPP4F2CA1
SCHEMBL7942 0.96
Benzene SCHEMBL4297098 0.96 ALDH1A1 (0.43) ALDH1A1TSHRDPP4F2CA1
SCHEMBL1778307 0.92
Hydrochloric Acid SCHEMBL5929655 0.92
Hydrochloric Acid SCHEMBL4462903 0.92 ALDH1A1 (0.40) ALDH1A1TSHRDPP4F2CA1
Ammonia Solution, Strong SCHEMBL22686091 0.92
SCHEMBL13370283 0.92
SCHEMBL16054548 0.92

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105829485-B Photocurable composition with adhesiveness 思美定株式会社 2018-10-12 CN disclosed
CN-103249762-A Addition-curable metallosiloxane compound DAICEL CORP 2013-08-14 CN disclosed
US-8124272-B2 polyvinyl acetal resin varnish which is so low in stimulus property, toxicity, environment-polluting property, offensive odor, and inflammability that no problem is caused in practical use, and which is high in safety, low in viscosity, and thus favorable in workability MITSUI CHEMICALS, INC. (JP) 2012-02-28 US disclosed
US-20080090145-A1 Polyvinyl Acetal Resin Varnish Gelling Agent, Nonaqueous Electrolyte Solution, And Electrochemical Device MITSUI CHEMICALS, INC. (JP) 2008-04-17 US disclosed