Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18428553 | 0.98 | CYP1A2 (0.52) | CYP1A2CYP2C9CYP2C19TLR8TSHR | |
| SCHEMBL30861903 | 0.98 | CYP1A2 (0.52) | CYP1A2CYP2C9CYP2C19TLR8TSHR | |
| SCHEMBL1979664 | 0.98 | CYP1A2 (0.52) | CYP1A2CYP2C9CYP2C19TLR8TSHR | |
| SCHEMBL10595283 | 0.98 | CYP1A2 (0.52) | CYP1A2CYP2C9CYP2C19TLR8TSHR | |
| SCHEMBL2252027 | 0.98 | CYP1A2 (0.52) | CYP1A2CYP2C9CYP2C19TLR8TSHR | |
| SCHEMBL11579460 | 0.89 | CYP1A2 (0.52) | CYP1A2CYP2C9CYP2C19TLR8TSHR | |
| SCHEMBL19980862 | 0.85 | MEN1 (0.55) | CYP1A2CYP2C9CYP2C19TLR8TSHR | |
| SCHEMBL15826627 | 0.85 | CYP1A2 (0.44) | CYP1A2CYP2C9CYP2C19TLR8TSHR | |
| SCHEMBL11225207 | 0.83 | SMPD1 (0.47) | CYP1A2CYP2C9CYP2C19TLR8TSHR | |
| SCHEMBL2367661 | 0.83 | TLR8 (0.54) | CYP1A2CYP2C9CYP2C19TLR8TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030162960-A1 | Colormetric sensor compositions and methods | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2003-08-28 | — | — | US | disclosed |
| US-6482949-B1 | Colormetric sensor compositions and methods | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2002-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030162960-A1 | Colormetric sensor compositions and methods | PAH, NISCH, SPR | CYP1A2 1387/4885CYP2C9 670/4885CYP2C19 953/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.