Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 11/20 | 0.52 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ALPL | P05186 | 1/20 | 0.47 |
| ▸ | ALPI | P09923 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | CNR2 | P34972 | 3/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7043236 | 0.88 | CNR1 (0.64) | CNR1 | |
| SCHEMBL7043397 | 0.82 | CNR1 (0.58) | CNR1HPGDALDH1A1HTTMEN1 | |
| SCHEMBL7044693 | 0.82 | CNR1 (0.64) | CNR1 | |
| SCHEMBL7042633 | 0.81 | CNR1 (0.52) | CNR1CNR2 | |
| SCHEMBL7045579 | 0.78 | CNR1 (0.57) | CNR1NPC1RAB9ACNR2 | |
| SCHEMBL6552432 | 0.78 | CNR1 (0.57) | CNR1NPC1RAB9ACNR2 | |
| SCHEMBL7044217 | 0.76 | CNR1 (0.57) | CNR1NPC1RAB9ACNR2 | |
| SCHEMBL7046180 | 0.75 | EPHX2 (0.50) | CNR1HPGDALDH1A1MEN1KMT2A | |
| SCHEMBL7043337 | 0.75 | CNR1 (0.56) | CNR1NPC1RAB9ACNR2 | |
| SCHEMBL7043451 | 0.73 | CNR1 (0.55) | CNR1NPC1RAB9ACNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003007887-A2 | SUBSTITUTED IMIDAZOLES AS CANNABINOID RECEPTOR MODULATORS | MERCK & CO., INC. (US) | 2003-01-30 | — | — | WO | claimed |
| WO-2003007887-A2 | SUBSTITUTED IMIDAZOLES AS CANNABINOID RECEPTOR MODULATORS | MERCK & CO., INC. (US) | 2003-01-30 | — | — | WO | disclosed |