Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 5/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7044203 | 0.88 | SMN1; SMN2 (0.51) | CNR1ALDH1A1POLBEPHX1NPC1 | |
| SCHEMBL7046180 | 0.88 | EPHX2 (0.50) | CNR1ALDH1A1EPHX1NPC1RAB9A | |
| SCHEMBL7045579 | 0.83 | CNR1 (0.57) | CNR1NPC1RAB9ACNR2 | |
| SCHEMBL7044680 | 0.83 | CNR1 (0.56) | CNR1ALDH1A1POLBEPHX1NPC1 | |
| SCHEMBL6552432 | 0.83 | CNR1 (0.57) | CNR1NPC1RAB9ACNR2 | |
| SCHEMBL7044205 | 0.82 | CNR1 (0.52) | CNR1ALDH1A1NPC1RAB9ACNR2 | |
| SCHEMBL7044217 | 0.82 | CNR1 (0.57) | CNR1NPC1RAB9ACNR2 | |
| SCHEMBL7042512 | 0.79 | CNR1 (0.58) | CNR1NPC1RAB9ACNR2SMN1; SMN2 | |
| SCHEMBL7043337 | 0.76 | CNR1 (0.56) | CNR1NPC1RAB9ACNR2 | |
| SCHEMBL7046586 | 0.76 | MAPT (0.40) | CNR1POLBNPC1RAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003007887-A2 | SUBSTITUTED IMIDAZOLES AS CANNABINOID RECEPTOR MODULATORS | MERCK & CO., INC. (US) | 2003-01-30 | — | — | WO | claimed |
| WO-2003007887-A2 | SUBSTITUTED IMIDAZOLES AS CANNABINOID RECEPTOR MODULATORS | MERCK & CO., INC. (US) | 2003-01-30 | — | — | WO | disclosed |