Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 8/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.40 |
| ▸ | GAA | P10253 | 5/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | NOX1 | Q9Y5S8 | 4/20 | 0.39 |
| ▸ | TERT | O14746 | 1/20 | 0.39 |
| ▸ | S100B | P04271 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 5/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL972682 | 0.93 | SNCA (0.46) | SNCAMAPTALDH1A1TDP1GAA | |
| Hydromethylthionine SCHEMBL109756 | 0.88 | SNCA (0.50) | SNCAMAPTALDH1A1TDP1GAA | |
| Hydromethylthionine SCHEMBL29356148 | 0.88 | SNCA (0.50) | SNCAMAPTALDH1A1TDP1GAA | |
| Hydromethylthionine SCHEMBL12592446 | 0.88 | SNCA (0.50) | SNCAMAPTALDH1A1TDP1GAA | |
| SCHEMBL5724694 | 0.88 | MAPT (0.39) | SNCAMAPTTDP1GAAHTT | |
| SCHEMBL9290137 | 0.87 | SNCA (0.41) | SNCAMAPTTDP1GAAHTT | |
| SCHEMBL10476547 | 0.87 | TERT (0.39) | SNCAMAPTALDH1A1TDP1GAA | |
| Hydromethylthionine SCHEMBL25199191 | 0.86 | SNCA (0.48) | SNCAMAPTALDH1A1TDP1GAA | |
| Hydromethylthionine SCHEMBL1577040 | 0.86 | SNCA (0.48) | SNCAMAPTALDH1A1TDP1GAA | |
| Hydromethylthionine SCHEMBL23683393 | 0.86 | SNCA (0.48) | SNCAMAPTALDH1A1TDP1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003007944-A1 | TREATMENT OF MACULAR EDEMA WITH PHOTODYNAMIC THERAPY | QLT, INC. (CA) | 2003-01-30 | — | — | WO | disclosed |
| US-4017313-A | Photosensitive composition containing a leuco dye, a photosensitizer, an aromatic aldehyde and a secondary or tertiary amine and the use thereof in a direct-print process | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1977-04-12 | — | — | US | disclosed |