Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | LCK | P06239 | 1/20 | 0.52 |
| ▸ | FYN | P06241 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | MYC | P01106 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.47 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13434226 | 0.92 | HTT (0.55) | HTTLCKFYNMAPTKDM4E | |
| SCHEMBL29191828 | 0.86 | LCK (0.57) | HTTLCKFYNMAPTKDM4E | |
| SCHEMBL1505272 | 0.86 | LCK (0.62) | HTTLCKFYNMAPTKDM4E | |
| SCHEMBL7048626 | 0.85 | HTT (0.63) | HTTMAPTKDM4EHPGDLMNA | |
| SCHEMBL14761140 | 0.84 | HTT (0.57) | HTTLCKFYNMAPTKDM4E | |
| SCHEMBL28625696 | 0.84 | LCK (0.55) | HTTLCKFYNMAPTKDM4E | |
| SCHEMBL20366921 | 0.83 | KDM4E (0.53) | HTTKDM4EHPGDLMNACYP3A4 | |
| SCHEMBL19331165 | 0.80 | HTT (0.46) | HTTLCKFYNMAPTKDM4E | |
| SCHEMBL12444087 | 0.80 | ALDH1A1 (0.56) | HTTLCKFYNMAPTKDM4E | |
| SCHEMBL3836141 | 0.80 | MAPT (0.64) | HTTLCKFYNMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3169662-B1 | SUBSTITUTED VINYL- AND ALKINYL-CYANOCYCLOALKANOLS AND VINYL- AND ALKINYL-CYANOHETEROCYCLOALKANOLS AS AGENTS TO COMBAT ABIOTIC PLANT STRESS | BAYER CROPSCIENCE AG (DE) | 2018-07-11 | — | — | EP | disclosed |
| US-20030236439-A1 | Non-steroidal analogs of 2-methoxyestradiol | ENTREMED, INC. | 2003-12-25 | — | — | US | disclosed |
| WO-2003063787-A2 | NON-STEROIDAL ANALOGS OF 2-METHOXYESTRADIOL | ENTREMED, INC. (US) | 2003-08-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030236439-A1 | Non-steroidal analogs of 2-methoxyestradiol | NR5A1, CCNB2, CYP17A1 | HTT 4824/4885LCK 3944/4885FYN 3759/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.