Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 3/20 | 0.44 |
| ▸ | CDK2 | P24941 | 3/20 | 0.44 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.44 |
| ▸ | DBF4 | Q9UBU7 | 2/20 | 0.44 |
| ▸ | CNR1 | P21554 | 9/20 | 0.43 |
| ▸ | DPP4 | P27487 | 2/20 | 0.43 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.43 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.39 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.39 |
| ▸ | CDK9 | P50750 | 2/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.39 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.39 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.39 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.39 |
| ▸ | PLK4 | O00444 | 1/20 | 0.39 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.39 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.39 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6553466 | 0.84 | ALOX5 (0.51) | CDC7DBF4CNR1DPP4DPP8 | |
| SCHEMBL7044437 | 0.81 | CNR1 (0.55) | CNR1CNR2ALPL | |
| SCHEMBL6552041 | 0.81 | CNR1 (0.56) | CNR1DPP4DPP8ALDH1A1MAPT | |
| SCHEMBL7044217 | 0.80 | CNR1 (0.57) | CNR1CNR2 | |
| SCHEMBL7043324 | 0.79 | TP53 (0.42) | CNR1 | |
| SCHEMBL7041732 | 0.79 | CNR1 (0.58) | CNR1CNR2ALPL | |
| SCHEMBL7046434 | 0.79 | CNR1 (0.57) | CNR1CNR2 | |
| SCHEMBL7045579 | 0.79 | CNR1 (0.57) | CNR1CNR2 | |
| SCHEMBL6552432 | 0.79 | CNR1 (0.57) | CNR1CNR2 | |
| SCHEMBL13722556 | 0.79 | CDC7 (0.46) | CDC7CDK2CCNE1DBF4CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003007887-A2 | SUBSTITUTED IMIDAZOLES AS CANNABINOID RECEPTOR MODULATORS | MERCK & CO., INC. (US) | 2003-01-30 | — | — | WO | disclosed |