Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.40 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.35 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3783641 | 0.98 | SIGMAR1 (0.44) | SIGMAR1CHRM3CHRM5PLA2G10PLA2G5 | |
| SCHEMBL17328038 | 0.98 | SIGMAR1 (0.44) | SIGMAR1CHRM3CHRM5PLA2G10PLA2G5 | |
| SCHEMBL4213475 | 0.98 | SIGMAR1 (0.44) | SIGMAR1CHRM3CHRM5PLA2G10PLA2G5 | |
| Bromide SCHEMBL22800758 | 0.97 | SIGMAR1 (0.43) | SIGMAR1CHRM3CHRM5PLA2G10PLA2G5 | |
| SCHEMBL4771744 | 0.94 | SIGMAR1 (0.47) | SIGMAR1CHRM3CHRM5PLA2G10PLA2G5 | |
| SCHEMBL3415840 | 0.92 | SIGMAR1 (0.49) | SIGMAR1CHRM3CHRM5PLA2G10PLA2G5 | |
| SCHEMBL583320 | 0.92 | SIGMAR1 (0.49) | SIGMAR1CHRM3CHRM5PLA2G10PLA2G5 | |
| SCHEMBL1149470 | 0.92 | SIGMAR1 (0.49) | SIGMAR1CHRM3CHRM5PLA2G10PLA2G5 | |
| SCHEMBL31505500 | 0.91 | CHRM3 (0.38) | SIGMAR1CHRM3CHRM5HSD17B10ALDH1A1 | |
| Bromide SCHEMBL583318 | 0.91 | SIGMAR1 (0.47) | SIGMAR1CHRM3CHRM5PLA2G10PLA2G5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114181164-A | Synthesis method and application of MRI contrast agent based on Fe (II) specificity | 武汉大学中南医院 | 2022-03-15 | — | — | CN | disclosed |
| CN-106890345-B | Contrast agent molecule targeting mitochondria as T2Use of contrast agents | 中国科学院苏州纳米技术与纳米仿生研究所 | 2020-09-01 | — | — | CN | disclosed |
| CN-106890345-A | A kind of contrast agent molecule of targetted mitochondria is used as T2The purposes of contrast agent | 中国科学院苏州纳米技术与纳米仿生研究所 | 2017-06-27 | — | — | CN | disclosed |
| EP-1419178-A1 | SOMATOSTATIN ANALOGUES AND THEIR USE SOMATOSTATIN ANALOGUES BINDING TO ALL SOMATOSTATIN RECEPTOR AND THEIR USE | University of Bern (CH) | 2004-05-19 | — | — | EP | disclosed |
| WO-2003014158-A1 | SOMATOSTATIN ANALOGUES AND THEIR USE SOMATOSTATIN ANALOGUES BINDING TO ALL SOMATOSTATIN RECEPTOR AND THEIR USE | UNIVERSITY OF BERN (CH) | 2003-02-20 | — | — | WO | disclosed |