Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | KDM6B | O15054 | 1/20 | 0.37 |
| ▸ | KDM5C | P41229 | 1/20 | 0.37 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.37 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.37 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28805186 | 0.86 | ALDH1A1 (0.43) | ALDH1A1TDP1KDM4EKDM6BKDM5C | |
| SCHEMBL79779 | 0.86 | — | — | |
| SCHEMBL5386710 | 0.86 | — | — | |
| SCHEMBL701554 | 0.83 | TP53 (0.44) | ALDH1A1TDP1TP53RNPEPCYP1A2 | |
| SCHEMBL10956052 | 0.83 | — | — | |
| SCHEMBL23467150 | 0.83 | TP53 (0.44) | ALDH1A1TDP1TP53RNPEPCYP1A2 | |
| Ammonia Solution, Strong SCHEMBL14935486 | 0.83 | — | — | |
| SCHEMBL15654871 | 0.83 | — | — | |
| SCHEMBL7133114 | 0.83 | — | — | |
| SCHEMBL10959727 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6808812-B2 | MIXTURE OF REACTION PRODUCT OF OXALIC ACID AND ORGANOMETALLIC COMPOUND AND AN ORGANOSILICON COMPOUND | ESSILOR INTERNATIONAL - COMPAGNIE GENERALE D'OPTIQUE (FR) | 2004-10-26 | — | — | US | disclosed |
| EP-1151048-B1 | ABRASION-RESISTANT COATING COMPOSITION, PROCESS FOR MAKING SUCH COATING COMPOSITION AND ARTICLE COATED THEREWITH | ESSILOR INT (FR) | 2002-10-16 | — | — | EP | disclosed |
| EP-1151048-A1 | ABRASION-RESISTANT COATING COMPOSITION, PROCESS FOR MAKING SUCH COATING COMPOSITION AND ARTICLE COATED THEREWITH | ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE (FR) | 2001-11-07 | — | — | EP | disclosed |
| US-20010020080-A1 | Abrasion-resistant coating composition, process for making such coating composition and article coated therewith | ESSILOR COMPAGNIE GENERALE D'OPTIQUE | 2001-09-06 | — | — | US | disclosed |
| US-6218494-B1 | REACTION PRODUCT WITH OXALIC ACID OF AT LEAST ONE ORGANOMETALLIC COMPOUND; EPOXYALKYL ORGANOALKOXYSILANE | ESSILOR INTERNATIONAL - COMPAGNIE GENERALE D'OPTIQUE (FR) | 2001-04-17 | — | — | US | disclosed |
| WO-2000029496-A1 | ABRASION-RESISTANT COATING COMPOSITION, PROCESS FOR MAKING SUCH COATING COMPOSITION AND ARTICLE COATED THEREWITH | ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE (FR) | 2000-05-25 | — | — | WO | disclosed |