SCHEMBL7044893

SCHEMBL7044893

O=C[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CP(=O)(O)O

nearest known ligand 0.52

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MPI P34949 1/20 0.44
GABBR2 O75899 1/20 0.32
GABBR1 Q9UBS5 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30472440 0.79 MPI (0.41) MPI
SCHEMBL29031898 0.79 MPI (0.41) MPI
SCHEMBL5059588 0.79 MPI (0.41) MPI
Demannose SCHEMBL361547 0.78 LMNA (0.48) MPI
Demannose SCHEMBL6533561 0.78 LMNA (0.48) MPI
Demannose SCHEMBL25381696 0.78 LMNA (0.48) MPI
Demannose SCHEMBL30973585 0.78 LMNA (0.48) MPI
Demannose SCHEMBL25380809 0.78 LMNA (0.48) MPI
Galactose SCHEMBL361095 0.78 LMNA (0.48) MPI
Demannose SCHEMBL23721809 0.78 LMNA (0.48) MPI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0721347-A1 AGENT AGAINST SENSITIVE, HYPERREACTIVE AND HYPOACTIVE STATES OF THE SKIN, FORMS OF ACNE, ATOPIC DERMATITIDES, PSORIASIS, PRURIGO, PHOTODERMATOSES, ICHTHYOSIS AND VIRAL INFECTIONS Beiersdorf Aktiengesellschaft (DE) 1996-07-17 EP claimed
WO-1995005852-A1 AGENT AGAINST SENSITIVE, HYPERREACTIVE AND HYPOACTIVE STATES OF THE SKIN, FORMS OF ACNE, ATOPIC DERMATITIDES, PSORIASIS, PRURIGO, PHOTODERMATOSES, ICHTHYOSIS AND VIRAL INFECTIONS BEIERSDORF AG (DE) 1995-03-02 WO claimed
EP-0797427-B1 AGENTS ACTING AGAINST HYPERREACTIVE AND HYPOACTIVE, DEFICIENT SKIN CONDITIONS AND MANIFEST DERMATITIDES BEIERSDORF AG (DE) 2003-05-14 EP disclosed
EP-1300138-A2 Agents effective against hyperreactive and hypoactive deficient skin conditions as well as manifest dermatitis Beiersdorf AG (DE) 2003-04-09 EP disclosed
EP-0797427-A1 AGENTS ACTING AGAINST HYPERREACTIVE AND HYPOACTIVE, DEFICIENT SKIN CONDITIONS AND MANIFEST DERMATITIDES Beiersdorf Aktiengesellschaft (DE) 1997-10-01 EP disclosed
EP-0721347-A1 AGENT AGAINST SENSITIVE, HYPERREACTIVE AND HYPOACTIVE STATES OF THE SKIN, FORMS OF ACNE, ATOPIC DERMATITIDES, PSORIASIS, PRURIGO, PHOTODERMATOSES, ICHTHYOSIS AND VIRAL INFECTIONS Beiersdorf Aktiengesellschaft (DE) 1996-07-17 EP disclosed
WO-1996018381-A1 AGENTS ACTING AGAINST HYPERREACTIVE AND HYPOACTIVE, DEFICIENT SKIN CONDITIONS AND MANIFEST DERMATITIDES BEIERSDORF AG (DE) 1996-06-20 WO disclosed
WO-1995005852-A1 AGENT AGAINST SENSITIVE, HYPERREACTIVE AND HYPOACTIVE STATES OF THE SKIN, FORMS OF ACNE, ATOPIC DERMATITIDES, PSORIASIS, PRURIGO, PHOTODERMATOSES, ICHTHYOSIS AND VIRAL INFECTIONS BEIERSDORF AG (DE) 1995-03-02 WO disclosed