Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | G6PD | P11413 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16757673 | 0.83 | NPSR1 (0.39) | MEN1MAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL6538771 | 0.81 | SMN1; SMN2 (0.38) | KDM4EALDH1A1NPSR1GAASMN1; SMN2 | |
| SCHEMBL4911171 | 0.81 | HTR1A (0.46) | MEN1MAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL29530991 | 0.81 | HTR1A (0.46) | MEN1MAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL28288419 | 0.80 | MAPT (0.52) | MEN1MAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL10911290 | 0.79 | DRD1 (0.42) | MAPTKDM4EALDH1A1L3MBTL1NPSR1 | |
| SCHEMBL947129 | 0.76 | PTGDR2 (0.38) | KDM4EALDH1A1HTTNPSR1GAA | |
| SCHEMBL10458170 | 0.76 | KDM4E (0.41) | MAPTKDM4EALDH1A1L3MBTL1HTT | |
| SCHEMBL513917 | 0.75 | SLC6A2 (0.42) | MEN1MAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL96814 | 0.75 | FFAR1 (0.46) | KDM4EALDH1A1L3MBTL1NPSR1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003018019-A2 | NEW USE OF CYCLIC COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-03-06 | — | — | WO | disclosed |