⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5389147 | 0.86 | — | — | |
| 2,5-Thiophenenedicarboxaldehyde SCHEMBL178830 | 0.86 | — | — | |
| SCHEMBL16533088 | 0.78 | ALDH1A1 (0.43) | — | |
| SCHEMBL20909478 | 0.77 | ALDH1A1 (0.40) | — | |
| SCHEMBL10757207 | 0.75 | ALDH1A1 (0.39) | — | |
| SCHEMBL28445298 | 0.74 | — | — | |
| SCHEMBL29493701 | 0.72 | DPP4 (0.39) | — | |
| SCHEMBL278904 | 0.72 | DPP4 (0.65) | — | |
| 2,5-Thiophenenedicarboxaldehyde SCHEMBL17477277 | 0.72 | ALDH1A1 (0.53) | — | |
| SCHEMBL1763234 | 0.72 | ALDH1A1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117835831-A | Flavor modulating composition | 玉米产品开发公司 | 2024-04-05 | — | — | CN | disclosed |
| EP-2649076-B1 | MACROCYCLIC INHIBITORS OF FLAVIVIRIDAE VIRUSES | GILEAD SCIENCES INC (US) | 2015-03-04 | — | — | EP | disclosed |
| EP-2649076-B1 | MACROCYCLIC INHIBITORS OF FLAVIVIRIDAE VIRUSES | GILEAD SCIENCES INC (US) | 2015-03-04 | — | — | EP | disclosed |
| US-8933015-B2 | Macrocyclic inhibitors of flaviviridae viruses | GILEAD SCIENCES, INC. (US) | 2015-01-13 | — | — | US | disclosed |
| US-20140023616-A1 | MACROCYCLIC INHIBITORS OF FLAVIVIRIDAE VIRUSES | SELCIA LIMITED (GB) | 2014-01-23 | — | — | US | disclosed |
| US-20140023616-A1 | MACROCYCLIC INHIBITORS OF FLAVIVIRIDAE VIRUSES | SELCIA LIMITED (GB) | 2014-01-23 | — | — | US | disclosed |
| EP-2649076-A1 | MACROCYCLIC INHIBITORS OF FLAVIVIRIDAE VIRUSES | Gilead Sciences, Inc. (US) | 2013-10-16 | — | — | EP | disclosed |
| US-8513184-B2 | Macrocyclic inhibitors of flaviviridae viruses | GILEAD SCIENCES, INC. (US) | 2013-08-20 | — | — | US | disclosed |
| US-8513184-B2 | Macrocyclic inhibitors of flaviviridae viruses | GILEAD SCIENCES, INC. (US) | 2013-08-20 | — | — | US | disclosed |
| US-20130022573-A1 | MACROCYCLIC INHIBITORS OF FLAVIVIRIDAE VIRUSES | SELCIA LIMITED (GB) | 2013-01-24 | — | — | US | disclosed |
| WO-2012078915-A1 | MACROCYCLIC INHIBITORS OF FLAVIVIRIDAE VIRUSES | GILEAD SCIENCES, INC. (US) | 2012-06-14 | — | — | WO | disclosed |
| WO-2012078915-A1 | MACROCYCLIC INHIBITORS OF FLAVIVIRIDAE VIRUSES | GILEAD SCIENCES, INC. (US) | 2012-06-14 | — | — | WO | disclosed |
| US-20030100681-A1 | Crosslinkable monomers for novel nonlinear optical polymers | CHICAGO, THE UNIVERSITY OF | 2003-05-29 | — | — | US | disclosed |
| US-20030092869-A1 | Novel nonlinear optical polymers | NAVY, SECRETARY OF THE UNITED STATES OF AMERICA | 2003-05-15 | — | — | US | disclosed |
| US-20030085388-A1 | Novel nonlinear optical compounds and polymers | CHICAGO, UNIVERSITY OF, THE | 2003-05-08 | — | — | US | disclosed |
| US-20030086666-A1 | Novel nonlinear optical polymers incorporating amines | CHICAGO UNIVERSITY OF, THE | 2003-05-08 | — | — | US | disclosed |
| WO-2003032072-A2 | CROSSLINKABLE MONOMERS FOR NOVEL NONLINEAR OPTICAL POLYMERS | THE UNIVERSITY OF CHICAGO (US) | 2003-04-17 | — | — | WO | disclosed |
| WO-2003007071-A2 | NOVEL NONLINEAR OPTICAL COMPOUNDS AND POLYMERS | THE UNIVERSITY OF CHICAGO (US) | 2003-01-23 | — | — | WO | disclosed |
| WO-2003007070-A1 | NOVEL NONLINEAR OPTICAL POLYMERS INCORPORATING AMINES | THE UNIVERSITY OF CHICAGO (US) | 2003-01-23 | — | — | WO | disclosed |
| WO-2003007069-A2 | NOVEL NONLINEAR OPTICAL POLYMERS | THE UNIVERSITY OF CHICAGO (US) | 2003-01-23 | — | — | WO | disclosed |