SCHEMBL2555645

SCHEMBL2555645

O=C(O)CCCCCCCCCCCCCCCc1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 1/20 1.00
▸ RXFP1 Q9HBX9 1/20 1.00
▸ HDAC1 Q13547 2/20 0.83
▸ HDAC2 Q92769 2/20 0.83
▸ HDAC3 O15379 1/20 0.83
▸ MAPK1 P28482 1/20 0.83
▸ ADRA1A P35348 1/20 0.83
▸ HDAC4 P56524 1/20 0.83
▸ SLC6A3 Q01959 1/20 0.83
▸ SMN1; SMN2 Q16637 1/20 0.83
▸ HDAC7 Q8WUI4 1/20 0.83
▸ HDAC10 Q969S8 1/20 0.83
▸ HDAC11 Q96DB2 1/20 0.83
▸ HDAC8 Q9BY41 1/20 0.83
▸ HDAC6 Q9UBN7 1/20 0.83
▸ HDAC9 Q9UKV0 1/20 0.83
▸ HDAC5 Q9UQL6 1/20 0.83
▸ KEAP1 Q14145 1/20 0.68
▸ ALOX5 P09917 1/20 0.67
▸ KDM4A O75164 1/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1008757 1.00 MAPT (1.00) MAPTRXFP1HDAC1HDAC2HDAC3
SCHEMBL770290 1.00 MAPT (1.00) MAPTRXFP1HDAC1HDAC2HDAC3
Phenylheptanoic Acid SCHEMBL535246 1.00 MAPT (1.00) MAPTRXFP1HDAC1HDAC2HDAC3
SCHEMBL1290374 1.00 MAPT (1.00) MAPTRXFP1HDAC1HDAC2HDAC3
SCHEMBL2552651 1.00 MAPT (1.00) MAPTRXFP1HDAC1HDAC2HDAC3
Phenylheptanoic Acid SCHEMBL7655508 1.00 MAPT (1.00) MAPTRXFP1HDAC1HDAC2HDAC3
SCHEMBL2551105 1.00 MAPT (1.00) MAPTRXFP1HDAC1HDAC2HDAC3
SCHEMBL2548842 1.00 MAPT (1.00) MAPTRXFP1HDAC1HDAC2HDAC3
SCHEMBL1007173 1.00 MAPT (1.00) MAPTRXFP1HDAC1HDAC2HDAC3
SCHEMBL2553009 1.00 MAPT (1.00) MAPTRXFP1HDAC1HDAC2HDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011124228-A1 A BIOCIDAL POLYOLEFIN YARN WITH 3-12 FILAMENTS VESTERGAARD FRANDSEN SA (CH) 2011-10-13 — — WO claimed
WO-2011124227-A1 BIOCIDAL ACID-ADJUSTED POLYMER WITH POLYPROPYLENE VESTERGAARD FRANDSEN SA (CH) 2011-10-13 — — WO claimed
US-20230265429-A1 SKELETAL MUSCLE DELIVERY PLATFORMS AND METHODS OF USE THEREOF Arrowhead Pharmaceuticals, Inc. 2023-08-24 — — US disclosed
US-20230265429-A1 SKELETAL MUSCLE DELIVERY PLATFORMS AND METHODS OF USE THEREOF Arrowhead Pharmaceuticals, Inc. 2023-08-24 — — US disclosed
US-20230226193-A1 LIPID CONJUGATES FOR THE DELIVERY OF THERAPEUTIC AGENTS Arrowhead Pharmaceuticals, Inc. 2023-07-20 — — US disclosed
US-11421223-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. (US) 2022-08-23 — — US disclosed
WO-2022056273-A1 LIPID CONJUGATES FOR THE DELIVERY OF THERAPEUTIC AGENTS Arrowhead Pharmaceuticals, Inc. (US) 2022-03-17 — — WO disclosed
US-20190309289-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2019-10-10 — — US disclosed
US-10370654-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. (US) 2019-08-06 — — US disclosed
US-20180320170-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2018-11-08 — — US disclosed
US-9944925-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. 2018-04-17 — — US disclosed
WO-2012162020-A1 STABILIZED BLENDS CONTAINING ANTIOXIDANTS THE LUBRIZOL CORPORATION (US) 2012-11-29 — — WO disclosed
WO-2012162027-A1 STABILIZED BLENDS CONTAINING FRICTION MODIFIERS THE LUBRIZOL CORPORATION (US) 2012-11-29 — — WO disclosed
WO-2011124227-A1 BIOCIDAL ACID-ADJUSTED POLYMER WITH POLYPROPYLENE VESTERGAARD FRANDSEN SA (CH) 2011-10-13 — — WO disclosed
US-7795207-B2 Lipopeptide compositions MERLION PHARMACEUTICALS GMBH (DE) 2010-09-14 — — US disclosed
US-20070219124-A1 Lipopeptide compositions COMBINATURE BIOPHARM AG (DE) 2007-09-20 — — US disclosed
EP-1751126-A1 ALKYL CARBAMATE-SUBSTITUTED BUTYROLACTONES SERVING AS LIPASE INHIBITORS Solvay Pharmaceuticals GmbH (DE) 2007-02-14 — — EP disclosed
WO-2005080366-A1 ALKYL CARBAMATE-SUBSTITUTED BUTYROLACTONES SERVING AS LIPASE INHIBITORS SOLVAY PHARMACEUTICALS GMBH (DE) 2005-09-01 — — WO disclosed
EP-1091958-A1 SALTS OF PAROXETINE SMITHKLINE BEECHAM PLC (GB) 2001-04-18 — — EP disclosed
WO-2000001692-A1 SALTS OF PAROXETINE SMITHKLINE BEECHAM PLC (GB) 2000-01-13 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230226193-A1 LIPID CONJUGATES FOR THE DELIVERY OF THERAPEUTIC AGENTS CPT1B, MUSK, MYLK2 MAPT 3973/4885RXFP1 3075/4885HDAC1 1399/4885
US-20070219124-A1 Lipopeptide compositions NOD2, IAPP, PTMS MAPT 3729/4885RXFP1 1379/4885HDAC1 4788/4885
US-20230265429-A1 SKELETAL MUSCLE DELIVERY PLATFORMS AND METHODS OF USE THEREOF MUSK, MYLK2, TNNC1 MAPT 4094/4885RXFP1 1262/4885HDAC1 1456/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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