SCHEMBL7045685 — predicted protein targets

Predicted protein targets (top 10)

	gene	UniProt	supporting neighbours	confidence
▸	ADRA2A	P08913	2/20	0.38

▸	MCHR1	Q99705	2/20	0.38

▸	NPY5R	Q15761	1/20	0.38

▸	TUBB3	Q13509	2/20	0.37

▸	ADRA1A	P35348	1/20	0.37

▸	HRH1	P35367	1/20	0.37

▸	HTR2B	P41595	1/20	0.37

▸	BCHE	P06276	2/20	0.35

▸	ACHE	P22303	2/20	0.35

▸	APP	P05067	1/20	0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL6463460	0.90	MCHR1 (0.41)	ADRA2AMCHR1NPY5RADRA1AHRH1
SCHEMBL6463472	0.90	MCHR1 (0.41)	ADRA2AMCHR1NPY5RADRA1AHRH1
SCHEMBL6876919	0.85	MCHR1 (0.41)	ADRA2AMCHR1NPY5RADRA1AHRH1
SCHEMBL6876906	0.85	MCHR1 (0.41)	ADRA2AMCHR1NPY5RADRA1AHRH1
SCHEMBL6460998	0.81	MCHR1 (0.38)	ADRA2AMCHR1NPY5RADRA1AHRH1
SCHEMBL6461007	0.81	MCHR1 (0.38)	ADRA2AMCHR1NPY5RADRA1AHRH1
SCHEMBL6878188	0.80	BCHE (0.46)	ADRA2AMCHR1NPY5RBCHEACHE
SCHEMBL6878189	0.80	BCHE (0.46)	ADRA2AMCHR1NPY5RBCHEACHE
SCHEMBL6877050	0.80	MCHR1 (0.41)	ADRA2AMCHR1NPY5RADRA1AHRH1
SCHEMBL6877060	0.80	MCHR1 (0.41)	ADRA2AMCHR1NPY5RADRA1AHRH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-1464335-A2	Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist	Taisho Pharmaceutical Co. Ltd. (JP)	2004-10-06	—	—	EP	disclosed