Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 5/20 | 0.55 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.55 |
| ▸ | ACE | P12821 | 1/20 | 0.51 |
| ▸ | CMA1 | P23946 | 13/20 | 0.51 |
| ▸ | CTRC | Q99895 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8770791 | 0.89 | F2 (0.62) | F2PRSS1ACECMA1CTRC | |
| SCHEMBL7050813 | 0.86 | F2 (0.52) | F2PRSS1ACECMA1CTRC | |
| SCHEMBL6438552 | 0.82 | F2 (0.55) | F2PRSS1ACECMA1CTRC | |
| SCHEMBL6438550 | 0.82 | F2 (0.55) | F2PRSS1ACECMA1CTRC | |
| SCHEMBL7359632 | 0.82 | ACE (0.55) | F2PRSS1ACECMA1CTRC | |
| SCHEMBL7622573 | 0.82 | CMA1 (0.62) | F2PRSS1ACECMA1CTRC | |
| SCHEMBL16576478 | 0.81 | F2 (0.65) | F2PRSS1ACECMA1CTRC | |
| SCHEMBL6412055 | 0.81 | ACE (0.66) | F2PRSS1ACECMA1CTRC | |
| SCHEMBL6412059 | 0.81 | ACE (0.66) | F2PRSS1ACECMA1CTRC | |
| SCHEMBL7087290 | 0.81 | ACE (0.66) | F2PRSS1ACECMA1CTRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0773955-B1 | NEW THROMBIN INHIBITORS, THEIR PREPARATION AND USE | BASF AG (DE) | 2003-04-16 | — | — | EP | disclosed |
| EP-0773955-A1 | NEW THROMBIN INHIBITORS, THEIR PREPARATION AND USE | BASF AKTIENGESELLSCHAFT (DE) | 1997-05-21 | — | — | EP | disclosed |