Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.52 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.52 |
| ▸ | ACE | P12821 | 1/20 | 0.52 |
| ▸ | CMA1 | P23946 | 15/20 | 0.52 |
| ▸ | CTRC | Q99895 | 1/20 | 0.47 |
| ▸ | CTSS | P25774 | 2/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | CTSB | P07858 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7359632 | 0.88 | ACE (0.55) | F2PRSS1ACECMA1CTRC | |
| SCHEMBL7045849 | 0.86 | F2 (0.55) | F2PRSS1ACECMA1CTRC | |
| SCHEMBL8780996 | 0.84 | ACE (0.57) | F2PRSS1ACECMA1CTRC | |
| SCHEMBL8770791 | 0.82 | F2 (0.62) | F2PRSS1ACECMA1CTRC | |
| SCHEMBL16576478 | 0.81 | F2 (0.65) | F2PRSS1ACECMA1CTRC | |
| SCHEMBL6438939 | 0.80 | F11 (0.62) | F2PRSS1ACECMA1CTRC | |
| SCHEMBL6438550 | 0.80 | F2 (0.55) | F2PRSS1ACECMA1CTRC | |
| SCHEMBL6438552 | 0.80 | F2 (0.55) | F2PRSS1ACECMA1CTRC | |
| SCHEMBL6438941 | 0.80 | F11 (0.62) | F2PRSS1ACECMA1CTRC | |
| SCHEMBL22409423 | 0.79 | ACE (0.77) | F2PRSS1ACECMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0773955-B1 | NEW THROMBIN INHIBITORS, THEIR PREPARATION AND USE | BASF AG (DE) | 2003-04-16 | — | — | EP | disclosed |
| EP-0773955-A1 | NEW THROMBIN INHIBITORS, THEIR PREPARATION AND USE | BASF AKTIENGESELLSCHAFT (DE) | 1997-05-21 | — | — | EP | disclosed |
| WO-1995035309-A1 | NEW THROMBIN INHIBITORS, THEIR PREPARATION AND USE | BASF AKTIENGESELLSCHAFT (DE) | 1995-12-28 | — | — | WO | disclosed |