Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1B | P00325 | 1/20 | 0.44 |
| ▸ | ADH1C | P00326 | 1/20 | 0.44 |
| ▸ | ADH1A | P07327 | 1/20 | 0.44 |
| ▸ | ADH4 | P08319 | 1/20 | 0.44 |
| ▸ | ADH7 | P40394 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 6/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL333321 | 1.00 | ADH1B (0.44) | ADH1BADH1CADH1AADH4ADH7 | |
| SCHEMBL333320 | 1.00 | ADH1B (0.44) | ADH1BADH1CADH1AADH4ADH7 | |
| Hydrochloric Acid SCHEMBL7046843 | 0.98 | ADH1B (0.42) | ADH1BADH1CADH1AADH4ADH7 | |
| SCHEMBL7045905 | 0.98 | ADH1B (0.47) | ADH1BADH1CADH1AADH4ADH7 | |
| SCHEMBL332488 | 0.98 | ADH1B (0.47) | ADH1BADH1CADH1AADH4ADH7 | |
| SCHEMBL332393 | 0.98 | ADH1B (0.47) | ADH1BADH1CADH1AADH4ADH7 | |
| SCHEMBL7047398 | 0.98 | ADH1B (0.47) | ADH1BADH1CADH1AADH4ADH7 | |
| SCHEMBL333039 | 0.98 | ADH1B (0.47) | ADH1BADH1CADH1AADH4ADH7 | |
| SCHEMBL332487 | 0.98 | ADH1B (0.47) | ADH1BADH1CADH1AADH4ADH7 | |
| SCHEMBL333359 | 0.98 | ADH1B (0.47) | ADH1BADH1CADH1AADH4ADH7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0996612-B1 | ALIPHATIC PROPARGYLAMINES AS CELLULAR RESCUE AGENTS | UNIV SASKATCHEWAN (CA) | 2003-04-09 | — | — | EP | claimed |
| EP-0996612-A2 | ALIPHATIC PROPARGYLAMINES AS CELLULAR RESCUE AGENTS | University of Saskatchewan Technologies Inc. (CA) | 2000-05-03 | — | — | EP | claimed |
| WO-1999003817-B1 | ALIPHATIC PROPARGYLAMINES AS CELLULAR RESCUE AGENTS | UNIV SASKATCHEWAN (CA) | 1999-07-01 | — | — | WO | claimed |
| WO-1999003817-A2 | ALIPHATIC PROPARGYLAMINES AS CELLULAR RESCUE AGENTS | UNIVERSITY OF SASKATCHEWAN TECHNOLOGIES INC. (CA) | 1999-01-28 | — | — | WO | claimed |
| EP-0996612-B1 | ALIPHATIC PROPARGYLAMINES AS CELLULAR RESCUE AGENTS | UNIV SASKATCHEWAN (CA) | 2003-04-09 | — | — | EP | disclosed |
| EP-0996612-A2 | ALIPHATIC PROPARGYLAMINES AS CELLULAR RESCUE AGENTS | University of Saskatchewan Technologies Inc. (CA) | 2000-05-03 | — | — | EP | disclosed |
| WO-1999003817-A2 | ALIPHATIC PROPARGYLAMINES AS CELLULAR RESCUE AGENTS | UNIVERSITY OF SASKATCHEWAN TECHNOLOGIES INC. (CA) | 1999-01-28 | — | — | WO | disclosed |
| US-5840979-A | USEFUL IN THE TREATMENT AND PREVENTION OF DISEASES IN WHICH CELL DEATH OCCURS BY APOPTOSIS | UNIVERSITY OF SASKATCHEWAN (CA) | 1998-11-24 | — | — | US | disclosed |